Capsular Bag Performance Of Two Hydrophobic Intraocular Lenses Of Different Design

The aim of this study is to analyze and compare the capsular bag performance, the PCO formation as well as lens axial
shift, tilt and centration of a new hydrophobic IOL with a sharp edge design (Enova GF3 IOL, VSY Biotechnology, Germany), compared to a standard monofocal hydrophobic IOL Tecnis 1-piece ZCB00 (Johnson & Johnson, USA) in a bilateral intra-individual comparison design

This was a randomized, controlled, double-masked trial in 90 eyes of 45 patients. The following examinations were performed: slitlamp examination, autorefraction, subjective refraction (UDVA,CDVA, UIVA, DCIVA), biometry with the IOLMaster 700, anterior segment OCT, retroillumination photography, Purkinjemeter, intraoperative
photography, as well as a surgeon and patient questionnaire (CATQUEST 9SF). 

So far 13 patients have been included (46.2% female, 53.8% male). The mean age was 69.9 ± 5.6 years.

The UDVA, CDVA and UIVA, increased significant in both groups 6 after moths (ENOVA p0.017, ZCB00 p0.012; ENOVA p0.0012, ZCB00 p0.011; ENOVA p0.0018, ZCB00 p0.027) The DCIVA increased significant only in the ZCB00 group (ENOVA p0.168, ZCB00 p0.026). 

The aqueous depth showed a mean of 3.85mm in the ENOVA group and 4.19mm in the ZCB00 group after 6 months, wich is a significant differnce (p0.012). There was no significant differnce within the groups. The mean tilt showed was 2.52° and 2.41° and the mean decentration in mm was 0.38 and 0.29 in the ENOVA group and the ZCB group respectively, witout a significant difference between the groups. 

The VA, IOL centration and IOL tilt does not appear different between the IOLs. Visual acuity was similar for the IOLs, except forD CIVA being slightly better for the control IOL. The ENOVA IOL has a similar capsular bag performance as thecontrol IOL. Detailed results of all patients will be presented.