PSEUDOEXFOLIATION SYNDROME: SPONTANEAOUS DISLOCATION OF THE CRYSTALLINE LENS IN THE ANTERIOR CHAMBER

seudoexfoliation syndrome (PEX) is a systemic disorder that leads to the accumulation of extracellular material in various ocular tissues,  which presents primarily via its characteristic ocular manifestations. PEX is considered an age-related microfibillopathy that affects different systemic organs and is characterized by a progressive chronic deposition and accumulation of extracellular greyish-white material in several organs.

spontaneous lens dislocation remains a rare complication

We report a case of a dislocation of the hole crystalline lens in the anterior chamber in a patient with pseudoexfoliation
syndrome

A 57 years old female patient presented to ophtalmological emergency department with acute onset of red and painful right eye along with decreased visual acuity. Her medical history was negative for a previous ocular trauma or any other pathological condition. Clinical examination found reduced visual acuity to
motion of fingers, conjunctival hyperaemia with high intraocular pressure, the crystalline lens was completely dislocated in
the anterior chamber . Deposits of pseudoexfoliation material were found in the controlateral eye with no signs of glaucoma. The dislocated lense was removed with favourable outcome, the implantation of an intraocular lens is planned and the patient is continued to be seen in regular follow-up

Pseudoexfoliation syndrome (PEX) is a systemic disorder of the extracellular matrix that presents primarily via its characteristic ocular
manifestations . Typically, white fibrillary residue on the anterior lens capsule and pupillary margin is observed, as are pupillary transillumination defects and pigmentation of the trabecular meshwork . Zonular weakness can be attributed to the deposition of pseudoexfoliative material on the zonular fibers and ciliary processes, resulting in a proteolytic disintegration of the zonule that can lead to spontaneous fragmentation . 

pseudoexfoliative syndrome is an ocular pathology that is difficult to treat. The treatment is based on the treatment of glaucoma as well as the various complications that can result from it.