MANAGEMENT OF A CONJUNCTIVAL LIMBIC TUMOR IN A CHILD WITH XERODERMA PIGMENTOSUM
Published 2024 - 28th ESCRS Winter Meeting
Reference: P159 | Type: Presented Poster & Poster | DOI: 10.82333/1y0m-0g59
Authors: Ayad Rima* 1 , Roukaya chahir 2 , zyad laftimi 2 , ghizlane daghouj 2 , loubna el maaloum 1 , bouchra allali 1 , asma el kettani 1
1Ophtalmologie,hopital 20 aout,Casablanca ,Morocco, 2hopital 20 aout,Casablanca ,Morocco
Purpose
Conjunctival squamous cell carcinoma is the most common malignant tumor of the conjunctiva. Its management remains a topical issue.
the aim of our work is to report the therapeutic management of this type of tumor in a child with Xeroderma Pigmentosum (XP).
Setting
We report a case of a 12-year-old child with XP who consults for conjunctival limbic tumor treated by total excision with application of mitomycin.
Methods
A 12-year-old child with Xeroderma Pigmentosum presented one year prior to admission with a rapidly enlarging right ocular conjunsctival limbic lesion.
Results
Results:
A 12-year-old child with Xeroderma Pigmentosum presented one year prior to admission with a rapidly enlarging right ocular lesion.
On admission, the visual acuity was 8/10, a pinkish, raised conjunctival limbic tumor, normal anterior segment and eye fundus ; the examination of the adelphic eye was unremarkable.
Initial management was based on surgical excision under general anaesthesia with a 2mm margin of healthy tissue using the "No Touch" technique.
Histological study revealed conjunctival squamous cell carcinoma in situ
Adjuvant treatment was based on the application of mitomycin C eye drops 0.04% in 2 courses of 15 days.
Progression was marked by tumor disappearance and corneal clearing.
Discussion:
Although there is no universal therapeutic consensus, mitomycin C eye drops are currently the standard treatment for conjunctival neoplasia. It is used either alone or in conjunction with surgery, as a single or repeated course of treatment, depending on the course of the disease.
Conclusion
The combination of surgical excision and mitomycin C eye drops is an effective, low-harm treatment for neoplastic pathology of the ocular surface. However, further studies are required to determine the optimal concentration and duration of this treatment.