CORRELATION BETWEEN A RASCH VALIDATED GERMAN STANDARDISED KERATOCONUS QUESTIONNAIRE (KORQ) AND CORNEAL IMAGING MODALITIES AND VISUAL QUALITY MEASUREMENTS

Published 2024 - 28th ESCRS Winter Meeting

Reference: P132 | Type: Submission | DOI: 10.82333/3wn7-fz19

Authors: Lisa Tasch* ¹ , Leon Pomberger ¹ , Mats Lundström ² , Klemens Waser ¹ , Haidar Khalil ¹ , Matthias Bolz ¹ , Nino Hirnschall ¹

¹Ophthalmology and Optometry,Johannes Kepler University,Linz,Austria;Ophthalmology and Optometry,Kepler University Clinic,Linz,Austria, ²Clinical Sciences for Ophthalmology,Lund University,Lund,Sweden

Purpose

To correlate results of patient reported outcome measures (PROMS) of the Keratoconus Outcomes Research Questionnaire (KORQ) with different corneal imaging modalities and visual quality measurements.

Setting

Department of Ophthalmology, Kepler University Clinic, Linz, Austria

Methods

In a first step the English KORQ was translated, validated and evaluated in a standardised fashion including a Rasch analysis. Therefore, a data-set of 100 patients (validation) and further 30 patients (evaluation) was included. In the next step correlation and regression models were used to find a potential correlation or interaction between the results of the KORQ and different parameters of Scheimpflug (Pentacam HR, Oculus, Germany) and OCT (MS-39, CSO, Italy) measurements, respectively. Furthermore, results of visual acuity testing and refraction parameters were included.

Results

The revised German KORQ met the criteria of Rasch analysis and showed excellent internal consistency reliability and convergent validity. The correlation between the KORQ score and various clinical measurements was examined using the Spearman’s correlation. A significant moderate correlation was observed between the D-value (r=0.237; p=0.006) and Kmax (r=0.162; p=0.065) values of the Pentacam. Inverse correlations were observed for thinnest pachymetry measured with MS-39 (r=-0.167; p =0.058) and best-corrected visual acuity (r=-0.210; p =0.016).

Conclusion

The revised German KORQ showed a moderately significant correlation between the measurements obtained with the Scheimpflug imaging device (D values) and an inverse correlation with the thinnest pachymetry measured with the MS-39 CSO. These results suggest that the KORQ effectively measures its intended constructs and links patient experiences with clinical data.