IMMUNOFLUORESCENCE OUTCOMES OF CORNEAL REGENERATION AFTER KERATOCONUS TREATMENT.
Published 2024 - 28th ESCRS Winter Meeting
Reference: P131 | Type: Submission | DOI: 10.82333/rg1w-4908
Authors: Faruk Semiz* 1 , Njomza Hima Musa 1 , Gokce Idil Semiz 2 , Ardian shabani 1 , Ceren Ece Semiz 1 , Zekeriya Alp Demirsoy 1 , Olcay Semiz 1 , Gamze Tanriverdi 3
1Opthtalmology,Eye Hospital,Pristina,Kosovo, 2Medical Faculty,Atilim Universitesi,Ankara,Türkiye, 3Histology and embryology,Cerrah Pasa Universitesi,Istanbul,Türkiye
Purpose
To examination of the lenticule using the immunofluorescence method after intrastromal implantation of the lenticule with SMILE in keratoconus patients.
Setting
Eye Hospital,Pristina,Kosovo
Methods
Forty-five eyes with advanced keratoconus (KCN) indicated for corneal transplantation were included in this study. Fresh myopic lenticular(FML) implants were placed in all eyes with SMILE surgery. Lenticular implants were removed from treated keratoconus patients after 2 and 3 years of surgery. These samples were examined and compared by immunofluorescence and light microscopy.
Results
The fragments were analyzed by the immunofluorescence method. Well-organized parallel layered structures were seen in all samples taken, and healthy keratocytes regenerative cells stem cells, and telocytes were observed.
Conclusion
Fresh myopic lenticular contains stem cells and telocytes that are involved in stromal regeneration.
ClinicalTrials.gov Identifier: NCT04591587