CORNEAL CROSS-LINKING IN RECURRENT KERATOCONUS: LONG TERM RESULTS
Published 2024 - 28th ESCRS Winter Meeting
Reference: P101 | Type: Presented Poster & Poster | DOI: 10.82333/hxzq-7834
Authors: Camilla Pagnacco* 1 , Erika Bonacci 2 , Mariacarmela Ventura 1 , Giorgio Marchini 1 , Emilio Pedrotti 1
1Department of Surgery, Dentistry, Maternity and Infant,University of Verona,Verona,Italy, 2Department of Engineering for Innovation Medicine,University of Verona,Verona,Italy
Purpose
To evaluate the long term effectiveness of corneal cross-linking (CXL) in patients with recurrent keratoconus (RKC) after keratoplasty.
Setting
The study was carried out at the Ophthalmic Unit of the University Hospital of Verona, Italy.
Methods
In this study, we enrolled patients with a history of penetrating or deep anterior lamellar keratoplasty performed for keratoconus who experienced keratoconus-recurrence. Long term (4 years) topographic (Galilei G4, Ziemer Ophtalmic Systems, Port, CH; CSO Vision Chart, CSO; Osiris-T CSO Italy), biomechanical ( Corvis ST, Oculus Optikgeräte GmbH, Wetzlar, GE) and visual (Snellen chart) changes were assessed in 14 patients (16 eyes) treated with accelerated-epi-off-CXL .
Results
At 4 years, biomechanical parameters (deformation amplitude ratio, inverse concave radius, applanation 1 length, applanation 2 length, highest concavity peak distance) did not significantly differ compared to baseline (p>0.05). Even though the difference in topographic maximum keratometry, pachymetric thinnest corneal thickness and topographic astigmatism were statistically significant (p<0.05), best corrected visual acuity and refraction were found stable and no further treatment was needed.
Conclusion
Although changing in topographic parameters, the accelerated-epi-off-CXL demonstrated to be effective in long term corneal biomechanical stabilization and refraction, proving to be able to delay or obviate new keratoplasties.