CANALOPLASTY PERFORMED WITH THE ITRACK MICROCATHETER TO REDUCE IOP IN UNCONTROLLED GLAUCOMA EYES

Purpose: To evaluate intraocular pressure (IOP) control and medication reduction in uncontrolled glaucoma eyes

Prospective multicenter cloud-based database

Methods: Eyes which received canaloplasty performed with an ab-interno approach with the iTrack microcatheter (Nova Eye Medical) with a preoperative IOP above 18mmHg (defined as uncontrolled IOP) were collated from the International Glaucoma Surgery Registry - IGSR. Primary endpoints were IOP reduction, control of IOP equal or below 18mmHg, and medication reduction.

Results: 145 eyes with a mean preoperative IOP (mmHg) of 23.8±5.5 and on 1.8±1.2 medications were recruited. IOP and medications were reduced to 14.6±3.5 and 16.3±5.3 and 1.2±1.4 and 0.9±1.3 at the 6- (n=60) and 12-month (n=31) follow-ups (p<0.001), respectively. 83.9% of the eyes were controlled (equal or below 18 mmHg) at the 12-month follow up. Mean IOP decreased in 93.5% of the eyes, while the number of medications decreased in 67.7% of the eyes, stayed the same in 25.8%, and increased in 6.5% of the eyes. Potentially related adverse events were: cystoid macular edema (2/145); hyphema >10% anterior chamber (3/145), and intraocular inflammation/uveitis (1/145).

Conclusion: Canaloplasty performed via an ab-interno technique resulted in a generic decrease of IOP in uncontrolled glaucoma eyes. The majority of baseline uncontrolled glaucoma eyes were IOP controlled following the canaloplasty procedure.