ESCRS - PP17.10 - Epithelial Remodeling And Cxl-Line Depth In Keratoconus Following Cxl Combined With Excimer Corneal Reshaping With The Athens Protocol

Epithelial Remodeling And Cxl-Line Depth In Keratoconus Following Cxl Combined With Excimer Corneal Reshaping With The Athens Protocol

Published 2023 - 41st Congress of the ESCRS

Reference: PP17.10 | DOI: 10.82333/581s-mt04

Authors: Athanasios Zisimopoulos* 1 , Anastasios John Kanellopoulos 2 , Alexandros John Kanellopoulos 1 , Despoina Karadimou 1 , Elena Konstantinidou 1 , Dimitrios Machairas 1

1Ophthalmology,Laservision Ambulatory Surgical Center,Athens,Greece, 2Ophthalmology,Laservision Ambulatory Surgical Center,Athens,Greece;Ophthalmology,NYU Med School,New York,United States

To evaluate epithelial remodeling and CXL-line depth in keratoconic eyes following surface ablation normalization combined with corneal crosslinking (Athens protocol)

 

LaserVision Ambulatory Eye Surgery Unit, Athens, Greece

Fourier-domain anterior segment optical coherence tomography (AS-OCT) was used to obtain in vivo 3-dimensional corneal and epithelial thickness maps and center, superior, inferior, maximum, minimum, mean, midperipheral, and variability data; as well as cross-section assessment of the average depth and width of the CXL derived intrastromal-line visualized

43 treated keratoconic eyes were evaluated over 2 years The mean overall epithelial thickness (ET) in um changed from 54.6 to 52.6, superior vs. inferior change in um: 56.9 and 52.3 to 53.3 and 52. ET change over cone center 45.1 to 53.2. All differences were statistically significant > 0.01. CXL line mean depth: 265um

These data confirm our previous findings of overall epithelial thickness normalization following CXL with the Athens Protocol. Increase to normal thickness over the cone center along with documentation of a deep CXL-line may serve as confirmation of the result efficacy along with corneal thickness and curvature stability over time.