Posterior Capsule Opacification With Two Hydrophobic Acrylic Intraocular Lenses: Vivinex Xy1 Vs Clareon Cna0t0: 3-Year Results Of A Randomized Trial
Published 2023 - 41st Congress of the ESCRS
Reference: PP13.14 | Type: Free paper | DOI: 10.82333/j0q0-g688
Authors: Christina Leydolt* 1 , Daniel Schartmüller 1 , Luca Schwarzenbacher 1 , Veronika Röggla 1 , Victor Danzinger 1 , Marcus Lisy 1 , Claudette Abela-Formanek 1 , Rupert Menapace 1
1Department of Ophthalmology,Medical University Vienna,Vienna,Austria
Purpose
To compare the incidence and intensity of posterior capsule opacification (PCO) and Nd:YAG capsulotomy rates between two similar open-loop single-piece hydrophobic acrylic intraocular lenses (IOLs) but differences in proprietary material characteristics and design features over a period of 3 years. A Randomized, prospective, patient- and examiner-masked clinical trial with intraindividual comparison
Setting
Department of Ophthalmology, Medical University Vienna
Methods
One hundred patients (200 eyes) had bilateral cataract surgery in both eyes and randomly received a Vivinex XY1 IOL in one eye and a Clareon CNA0T0 IOL in the fellow eye. Follow-up examinations were performed three years after surgery. Digital retroillumination images were taken of each eye. The amount of posterior capsule opacification (score: 0 – 10) was assessed subjectively at the slit-lamp and objectively using automated image analysis software (AQUA).
Results
67 of 100 patients were available for the 3-years follow-up examination. The objective PCO score of the Vininex XY1 IOLs was 1.0 ± 1.0 compared to the PCO score of 1.5 ± 1.2 for the Clareon CNA0T0 IOLs (p < 0.001). 6.0% of patients had a neodymium:yttrium-aluminium-garnet (Nd:YAG) capsulotomy in the Vininex XY1 eye, and 7.5% had a capsulotomy in the Clareon CNA0T0 eye (p = 0.73) three years postoperatively.
Conclusions
Both hydrophobic acrylic IOLs showed low PCO and YAG rates with a small but significant favour of the Vivinex XY1 IOL compared to the Clareon CNA0T0 IOL. The interaction of various factors such as hydrophobic material, smooth optic surface and sharp posterior optic edge is the major key for PCO prevention.