Corneal Allogenic Intrastromal Ring Segments (Cairs) For Keratoconus: A French Case Series
Published 2023 - 41st Congress of the ESCRS
Reference: PP11.13 | Type: Free paper | DOI: 10.82333/4enk-n275
Authors: Alain Saad* 1 , Nicole Mechleb 1 , Roxane Flamant 1 , Sina Elahi 1 , Adrien Mazharian 1 , Wassim Ghazal 1 , Filippo Fabro 1 , Christophe Panthier 1 , Shady Awwad 2 , Damien Gatinel 1
1Rothschild Foundation Hospital,Paris,France, 2American University of Beirut,Beirut,Lebanon
Purpose
Purpose: To describe the results of corneal allogenic intrastromal ring segments (CAIRS) for the treatment of keratoconus (KC).
Setting
Rothschild Foundation Hospital Laser Center
Methods
Methods: CAIRS trephined from donor cornea were implanted into femtosecond laser-dissected channels at 5 or 6 mm in the cornea of patients with keratoconus. Different techniques were used to insert the CAIRS into the recipient cornea. All cases were recorded.
Results
Results: Fifteen patients (15 eyes) with stage 2 to 4 KC (Amsler-Krumeich grading) underwent CAIRS implantation. At 1 month post-operatively, best corrected visual acuity significantly improved, in all patients, from a mean of 0.43 LogMAR to 0.09 LogMAR. Spherical equivalent, and astigmatism were reduced from -6.03 ± 4.7D to 0.04 ± 1.39D and from -4.92 ± 2.58 D to -2.72 ± 2.53D. Topographic astigmastim, and mean and steepest keratometry were significantly reduced from 56.27 ± 5.4 D and 47.5 ± 3.89 D pre-operatively to 53.96 ± 6.86 D and 41.6 ± 4.09 D at 1 month post-operatively. Corneal higher order aberrations and coma at 6mm decreased from a mean of 16.9mm and 3.5mm to 4.9mm, and 2.0mm respectively.
Conclusions
Conclusions: CAIRS implantation may be a simple, safe, and effective option for treating keratoconus of different stage and pachymetry. Further studies are recommended to determine long-term outcomes and fine-tune implantation nomograms.