ESCRS - PP09.13 - Effect Of Pretreatment With Lubricant Drops On Femtolasik Induced Dry Eye Symptoms. A Prospective, Masked, Controlled Study.

Effect Of Pretreatment With Lubricant Drops On Femtolasik Induced Dry Eye Symptoms. A Prospective, Masked, Controlled Study.

Published 2023 - 41st Congress of the ESCRS

Reference: PP09.13 | Type: Free paper | DOI: 10.82333/5wjp-6a15

Authors: Miguel Angel Teus* 1 , Rafael Cañones-Zafra 2 , Cristina Muñiz-da Costa 2 , Miriam Alonso-Cstellanos 2

1Novovision clinic,madrid,Spain;Ophthalmology,Universidad de Alcala,Alcala de Henares,Spain, 2Novovision clinic,madrid,Spain

Purpose

To report the interim results of an ongoing study on ocular comfort (OSDI), and objective tear film parameters, osmolarity (Tear Lab) and NIBUT (Keratograph) in myopic patients randomized to use topical lubricants Systane hydration MDPF for all patients) either beginning one week prior to surgery (Pre-group) or just after surgery (Post-group).

Setting

Private clinical practice located in Madrid, Spain

Methods

A prospective, single-masked, randomized, comparative study. Refractive error and UDVA, BCVA, Tear osmolarity, OSDI test, and Keratograph analysis of the tear film were performed by a masked examiner before and 1 day, 1 week, and 1 month after FS-LASIK performed to correct myopia in both Pre and Post groups. A total of 60 eyes per group will be analyzed. The interim results reported now correspond to the 24 eyes in Pre and 22 eyes in the Post groups.

Results

Mean age was 32.5±5.6 and 32.6±4.7 years, mean preop sphere was -2.48±2.2 and 2.76±1.1 D in Pre and Post groups respectively, (p>0.05). In addition, no statistically significant difference was found in preoperative OSDI, tear osmolarity, or NIBUT between both groups.

We only found statistically significant differences in the OSDI score, and NIBUT (4.57±2.5 vs 12.5±7.2 and 11.6±8.7 vs 6.8±2.9 secs respectively, p<0.05) at the 1-month postop in the Pre and Post groups, respectively.

Conclusions

Pretreatment with Systane Hydration MDPF seems to improve both the patient comfort and the tear film stability one month after FS-LASIK was performed to correct myopia. These results suggest that one week of pretreatment with topical lubricants could be considered in routine FS LASIK cases.

Financial disclosure of all authors: Miguel Teus: Alcon (research grants). The study was funded by an investigator-initiated trial grant (#67952279) from Alcon.