Clinical And Laboratory Performance Of A New Hydrophobic Biaspheric Extended Depth Of Focus Intraocular Lens

To analyze the optical performance and visual outcomes a new biaspheric phase-ring extended depth of focus intraocular lens (IOL), Asqelio^TM EDoF Toric (AST Products Inc, Billerica, MA).

Fernandez-Vega Ophthalmology Institute, Oviedo, Spain

IOLs were analyzed by means of through-focus MTF at 50 cycles/mm using an optical bench system (PMTF, Lambda-X, Belgium), and its clinical performance was assessed in 50 subjects bilaterally (100 eyes) implanted 3 months after surgery. Residual refractive error, visual performance at distance, intermediate and near, as well as defocus curves were obtained for each patient. The mean age of the patients was 73.1±7.0.

Through-focus MTF shows a peak for distance with a progressive decline with vergence that corresponds well with the clinical performance observed through the defocus curves obtained. In the clinical study, in the postoperative period at 6 months, the mean distance corrected visual acuity (DCVA) was 0.94±0.21 (Snellen scale). Mean binocular DCVA at 66- 50- and 40-cm (defocus curve) was 0.8, 0.7, and 0.63, respectively. The contrast sensitivity (Optec-6500) were within normal limits. In the vision quality questionnaire (Catquest-9SF), 100% of the patients reported being quite satisfied or very satisfied with their vision. Regarding the presence of dysphotopsia (McAlinden), 12% of the patients reported having only mild starburst.

Both optical bench and clinical outcomes show this new EDoF IOL as an efficient method for obtaining good visual performance from far to intermediate distances, and in some cases functional vision at all distances.