Assessing Patient Benefits Of Monofocal Aspheric Iol In Providing Functional Intermediate Visual Acuity Based On A Pooled Analysis Of Two Large Randomized Controlled Trials

Assess and report the visual outcomes and potential intermediate vision acuity benefits of patients implanted with an AcrySof IQ aspheric intraocular lens (IOL) from 2 large randomized controlled trials (RTCs). Reporting the defocus curve, and patient questionnaire outcomes.  

Two prospective, controlled clinical trials conducted in Australia, Europe, and North America

Analyze the results of a pooled analysis of patients binocularly implanted with the AcrySof IQ SN60WF aspheric monofocal IOL targeting emmetropia. At 6 months binocular MRSE, uncorrected and best-corrected distance visual acuity (UCDVA and BCDVA, respectively) were collected. Defocus curve measures were generated, along with distance corrected intermediate visual acuity (IVA) at 66cm. Patient reported spectacle independence data was collected. The report includes a large sample of patients sourced from 2 prospective, controlled clinical trials conducted in Australia, Europe, and North America using comparable clinical methods and validated questionnaires.

Based on pooled data for 233 binocular patients, at 6 months, mean (SD) binocular UCDVA, BCDVA and MRSE were -0.019 (0.110) logMAR, -0.088 (0.082) logMAR and 0.036 (0.371) Diopters respectively. Defocus curve showed a wide landing zone and expected excellent visual acuities. Mean (SD) binocular uncorrected IVA (66cm) was 0.125 (0.145) logMAR (20/25 Snellen), with 82.5% of patients achieving uncorrected functional IVA of better than or equal to 20/32. “Very good” or “good” uncorrected vision was reported by 92.2% of patients at distance and 62.9% patients at intermediate. Percentages of patients reporting “never wearing glasses” at 6 months were 86.4% at distance and 41.4% at intermediate.

Based on analyzed data from a large pool of bilaterally implanted patients from multiple regions, the AcrySof IQ aspheric IOL provides excellent distance vision, while the defocus curve and discrete acuity data demonstrate functional-IVA capabilities of this aspheric monofocal IOL.