Optimization Of Treatment Of Inflammatory Diseases Of The Anterior Surface Of The Eye
Published 2023 - 41st Congress of the ESCRS
Reference: PO0818 | DOI: 10.82333/jztm-5v64
Authors: Azamat Yusupov 1 , Muyassar Karimova 1 , Zebiniso Niyazova* 1 , Dilbarhon Makhkamova 1
1ophthalmology,Republican Specialized scientific practical center of eye microsurgery,Tashkent,Uzbekistan
To study the effectiveness of the ophthalmic film "Novacel Ziyo" in the treatment of inflammatory diseases of the anterior part of the eye.
The study was conducted in the Department of eye Diseases of the Clinical Hospital of Emergency Medical Care in Tashkent.
25 patients with lesions of the anterior surface of the eye were examined. The average age was 35±9.2 years. Men made up 56%, women 44%. The ophthalmic film "Novacel Ziyo" developed by us has the following properties: biocompatibility, biodegradability, high sorption activity, water vapor permeability, elasticity, strength, presence of antimicrobial properties, absence of cytotoxicity, pyrogenic and toxic effects. To study the effectiveness of the Novacel Ziyo ophthalmic film, we selected a group of volunteers who made up the main group I (10 patients), who were treated using the film, group II consisted of 15 patients who were treated using traditional methods of treatment.
The ophthalmic film "Novacel Ziyo" with antimicrobial properties is applied to the damaged surface of the cornea. The assessment of the degree of activity of the inflammatory reaction of the eyes was carried out according to a 3-point system according to Maychuk Yu. F. and Vakhova E. S. according to the following signs: narrowing of the ocular slit, the amount and nature of the discharge, pericorneal and conjunctival injection, conjunctival edema, conjunctival infiltration, corneal condition, corneal ulceration. The results of the study showed the effectiveness of using the film on day 7 for a sharp decrease in the clinical manifestations of the inflammatory eye reaction by 1.5 times in patients of group I compared with group II.
Preliminary results of our studies on volunteers confirm the bactericidal activity of the domestic ophthalmic film for the treatment of diseases of the ocular surface of the eyes.