Pigmented Carcinoma In Situ: A Case Report

We wish to highlight the specificities of the management of a rare conjunctival tumor, squamous cell carcinoma in situ, which, when respected, allows a long-term remission.

We report the observation of a 47-year-old patient, who presented in our training for a rapidly evolving conjunctival tumor, having benefited from a surgical excision revealing a squamous cell carcinoma in situ, completed by an adjuvant chemotherapy based on Mitomycin-C 0,04 %

This is a 47 year old patient, without any particular pathological history, consulted for the rapid appearance in one month of a conjunctival swelling in the right eye, the examination at admission objective a visual acuity at 10/10, the examination with the slit lamp finds a round conjunctival growth measuring 6 /5 mm, The rest of the examination as well as the contralateral eye was unremarkable.

An optical coherence tomography of the anterior segment was performed, with sections in the limbo-corneal region, which did not show any stromal infiltration of the tumor. In view of this aspect, a neoplasia was strongly indicated and a surgical removal was performed with intraoperative use of Mitomycin 0.04%. Histopathological examination was in favor of a pigmented carcinoma in situ.

Mitomycin-based chemotherapy was used to avoid the risk of local recurrence. The evolution was favorable without recurrence during the entire surveillance period.

Les carcinomes épidermoïdes in situ de la conjonctive demeurent des tumeurs de bon pronostic, à faible risque de récidive d'autant plus que l'exérèse a été complète, la cryothérapie faite et l'adjonction postopératoire d'anti mitotiques évaluée en fonction du cas. Un bilan préopératoire est licite et conditionne la prise en charge ainsi que le pronostic