Visual And Refractive Outcomes And Complications Of Customized Prk Plus Accelerated Cxl In Early Kcn Versus Customized Prk In Myopic Subjects.

To compare the safety, efficacy, stability and predictability of wavefront guided PRK plus accelerated CXL in early KCN with customized PRK in patients with low myopia.

Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences and Iranian Eye Clinic, Tehran, Iran.

Thirty-nine eyes of 39 patients with stable early keratoconus and 44 eyes of 44 patients with myopia were included. After 6.0 months Uncorrected (UDVA) and corrected (CDVA), distance visual acuity, refractive outcomes, and complications were evaluated.

At six months UDVA, CDVA and refractive error improved significantly in both groups(P<0.05). Mean SE refraction improved from -2.39 D to -0.13 in KCN group and from -2.28 D to +0.06 in PRK group. Mean cylinder improved from -1.35 to -0.54 D and -0.84 to -0.04 D respectively. Nine eyes (23.1%) in KCN group develop corneal haze at 2 months postoperation that improved at 6.0 months post-0p. Sixteen eyes (41%) in KCN group gain 1-4 lines of UDVA. The safety and efficacy index were 1.10, 1.00 and 98.1%, 100% in KCN and PRK groups respectively.

The visual and refractive outcomes of WFG-PRK plus accelerated CXL in stable early KCN is promising and comparable with customized PRK in normal myopic subjects. Both techniques appear safe and effectively improved the UDVA, CDVA and refractive error.