ESCRS - PO0667 - Pneumatic Versus Manual Pdek. A Refractive, Visual And Epidemiological Analysis

Pneumatic Versus Manual Pdek. A Refractive, Visual And Epidemiological Analysis

Published 2023 - 41st Congress of the ESCRS

Reference: PO0667 | Type: Free paper | DOI: 10.82333/wvht-jx06

Authors: Michael Tsatsos* 1 , Ioannis Giachos 2 , Anastasia Tsiogka 2 , Nikolaos Ziakas 1

1Ophthalmology,Aristotle Univeristy,Thessaloniki,Greece, 2Ophthalmology,University of Athens,Athens,Greece

Purpose

Predescemetic Endothelial Keratoplasty (PDEK) shares advantages of both DMEK and DSEK such as very fast visual rehabilitation and some relative ease of handling whilst being able to use grafts from young donors; however the creation of PDEK grafts via pneumatic standardisation remains an area of controversy.

We aim to compare the characteristics 20 consecutive patients undergoing pneumatic and manual PDEK and assess the visual outcome at different time intervals.

Setting

2nd Ophthalmology Department

Papageorgiou Hospital

Aristotle University Hospital

Thessaloniki, GReece

Methods

10 consective patients from each group (pneumatic and manual PDEK) were retrospectively analysed.

Patients were assessed for Best Corrected Visual Acuity and change Refraction at 1, 3, 6, 9 and 12 months post-operatively.

The normal distribution of demographic and clinical information was assessed by plots (histogram and probability graphs) and corresponding statistical tests (Kolmogorov–Smirnov/Shapiro–Wilk test). We created different diagrams to show correlations among studied variables. Statistical significance was set at P<0.05. Analysis was conducted in the Stata statistical software package version 13 (STATA Corp., College Station, TX).

Results

20 patients, 10 patients that underwent PDEK after pneumatic preparation of the corneal graft and 10 after manual preparation of the corneal graft, were enrolled in the study. Overall, (33.33%) of the subjects were males and (66.67%) were females with a mean age of 69.83± 6.45 years (range 59-80 years). 

Mean Difference of Refractive Change was 0.375±0.1 for Pneumatic PDEK and 0.67±0.1 for Manual PDEK (p=0.0404)

BCVA at  12 Months was 0.86±0.03 and 0.9±0.03 (p=0.1412) for pneumatic and Manual PDEK respectively

Graft Thickness at 12 Months  was also no different between pneumatic and Manual PDEK 7.3±0.4 8.67±1.6 (p=0.2203)

 

 

Conclusions

The was no singinificant difference in BCVA between Pneumatic and Manual PDEK in any time interval (1,3, 6, 9 or 12 months). Graft thickness measured at 6 and 12 months postoperatively showed no difference between pneumatic and MAnual PDEK. 

There was a significant difference between the induced refractive change with manual PDEK inducing a higher degree of hyperopia. 

Manual PDEK appears to be a repeatable alternativeto pneumatic PDEK whilst leading to a similar non-inferior visual outcome.