Six-Month Visual Performance Outcomes Of A Purely Refractive Extended Depth Of Focus Intraocular Lens
Published 2023 - 41st Congress of the ESCRS
Reference: PO0511 | DOI: 10.82333/n7zw-m554
Authors: Chandra Bala* 1 , Dean Corbett 2 , Srividhya Vilupuru, 3 , Aixa Alarcon 4 , Linda Tsai 3
1PersonalEyes,Sydney,Australia, 2Corbett Vision,Auckland,New Zealand, 3Johnson & Johnson,California,United States, 4Johnson & Johnson,Groningen,Netherlands
To evaluate the visual performance of a new purely refractive extended depth of focus (EDF) IOL and compare to a standard aspheric monofocal IOL according to the ANSI EDF standard.
A comparative evaluation of visual outcomes from two prospective, randomized, subject/evaluator masked clinical studies conducted in Australia/New Zealand (6 sites) and United States (10 sites).
Refractive EDF IOL (Model DEN00V) was bilaterally implanted in 60 subjects and monofocal IOL (Model ZCB00) was bilaterally implanted in 131 subjects. Monocular distance-corrected (DC) visual acuities at far (4m), intermediate (66 cm) and near (40 cm) were evaluated at the 6- month postoperative visit. Spontaneous reports of visual symptoms experienced by the subject are reported. Visual acuity is presented as mean logMAR and in Snellen notation.
Monocular DCIVA in the EDF eyes is clinically significant with 2-lines improvement in comparison to the monofocal eyes. 82.2% of eyes achieved 0.20 logMAR or better monocular DCIVA, i.e., 63.7% more than the monofocal eyes. The range of vision at 0.20 logMAR from the monocular defocus curve was 0.60D larger in the EDF eyes when compared to monofocal eyes. Mean monocular BCDVA was similar in the EDF and monofocal eyes with -0.06 vs. -0.05
logMAR (~6/4.8), respectively.
The new purely refractive EDF IOL fulfills the criteria of an EDF IOL according to the ANSI EDF Standard providing excellent intermediate vision with no compromise to quality of distance vision.