Micro-Perimetry Combined With Mferg To Monitor The Correlation Changes Before And After Multifocal Lens Implantation

Combined with microperimetry and multifocal electroretinogram, the visual quality of cataract patients after phacoemulsification combined with single-focus and trifocal intraocular lens implantation was evaluated.

Cataract is the leading cause of blindness, and its incidence has been increasing year by year with the population ageing of our country. At present, the traditional single-focus intraocular lens implantation can not meet the needs of multi-line-of-sight correction and lens removal, so it is urgent to seek preventive and therapeutic measures to improve the visual quality.

Patients (aged 37-75 years) with intraocular lens implantation who attended the ophthalmology department of the Nanjing Medical University Affiliated Wuxi Second People's Hospital from June 2021 to September 2022 were included. After obtaining the informed consent of the patients, the visual quality of the patients undergoing single-focus and triple-focus intraocular lens implantation was compared before and after surgery, the best corrected visual acuity (BCVA) , microperimetry (the fixation rate of 2 ° and 4 ° in the macula area, the retinal light sensitivity of 10 ° in the macula area) and multifocal electroretinogram (the amplitude density and peak time of P1 and N1 waves in R1 Loop) were included.

BCVA in trifocal group was better than that in monofocal group 3 months after operation (P=0.021, P < 0.05). Three months after trifocal surgery, the 2 fixation rate (P=0.030, P＜0.05) and 4 fixation rate (P=0.035, P＜0.05) in macular area were better than those in monofocal group. The visual acuity was improved at different time points after implantation in trifocal group and monofocal group (P < 0.01). The average amplitude density of N1 wave in trifocal group increased after operation (P=0.015, P＜0.05). There was a positive correlation between preoperative BCVA and the peak time of preoperative N1 wave in trifocal group (r=0.592, P < 0.05). 

The combined evaluation of microperimetry and multifocal electroretinogram can provide the basis for the evaluation of visual quality of patients.