ESCRS - PO0482 - A Prospective, Randomized, Comparative, Double Masked Study Comparing Intra-Operative Efficiencies And Post-Operative Outcomes Of Two Phacosystems

A Prospective, Randomized, Comparative, Double Masked Study Comparing Intra-Operative Efficiencies And Post-Operative Outcomes Of Two Phacosystems

Published 2023 - 41st Congress of the ESCRS

Reference: PO0482 | Type: Free paper | DOI: 10.82333/mjet-ww68

Authors: Saurabh Choudhry* 1 , Reena Manchanda Choudhry 1

1Cataract and Refractive,ICARE Eye Hospital and Postgraduate Institute,NOIDA,India

Purpose

Evaluation of post-operative and intra-operative outcomes of two different phacosystems namely Legion and Laureate

Setting

A prospective, randomized, double masked, comparative study where a single surgeon operates on equal number of eyes with
Nuclear Opalescence grade II & III cataracts in both the arms

Methods

108 eyes from 108 subjects, aged between 40-75 years, with uncomplicated nuclear sclerosis grade II & III cataracts, were randomized to undergo phacoemulsification either with the Legion or Laureate phacosystems. Each patient was followed up for one month and evaluated for post-operative outcomes such as central corneal thickness, anterior chamber cells and flare , endothelial cell counts which were recorded on day 1 & month 1 and compared to pre-operative values. Inter-group comparison was done to analyze the intraoperative results  and outcomes between the two arms.

Results

There is a statistically significant difference (p value 0.0008) in mean difference in Central Corneal Thickness (CCT) [pre-op and post-op day 1] between the groups (Leg;27.647, Lau;35.336, Mean diff;7.689). Other secondary end points, mean difference in the Endothelial Cell Count (ECC) [pre-op and post-op month 1] was also statistically significant (Leg; -66.275, Lau; -95.826, Mean diff; -29.551, p value <0.0001) favoring the Legion arm. There was statistically significant difference in the mean case time (Leg; 11.65s, Lau; 12.90s, p value 0.0013) and mean BSS volume usage (Leg; 138.6ml, Lau; 182.9ml, p value <0.0001) between the groups.

Conclusions

Better outcomes with Legion with Ozil handpiece which delivers torsional ultrasound over Laureate with a traditional ultrasound provides superior safety outcomes in corneal protection (mean CCT and mean ECC) and surgery efficiency outcomes (mean case time and mean BSS volume usage).