Comparison Of Endothelial Cell Loss In Diabetic Patients After Conventional Phacoemulsification And Femtosecond Laser-Assisted Cataract Surgery
Published 2023 - 41st Congress of the ESCRS
Reference: PO0359 | Type: Free paper | DOI: 10.82333/tt9t-3331
Authors: João Carlos Gonçalves Cruz 1 , Celso Busnelo moreno 1 , Paula Virginia Brom dos Santos Soares 1 , Bernardo Kaplan Moscovici* 2 , Guilherme Novoa Colombo-Barboza 3 , Luiz Roberto Colombo-Barboza 4 , Marcello Novoa Colombo-Barboza 5
1Hospital Oftalmológico Visão Laser,Santos,Brazil, 2Hospital Oftalmológico Visão Laser,Santos,Brazil;Department of Ophthalmology and Visual Sciences,Universidade Federal de São Paulo (EPM/UNIFESP),São Paulo,Brazil, 3Hospital Oftalmológico Visão Laser,Santos,Brazil;Department of Ophthalmology and Visual Sciences,Universidade Federal de São Paulo (EPM/UNIFESP),São Paulo,Brazil;Universidade Metropolitana de Santos (UNIMES),Santos,Brazil, 4Hospital Oftalmológico Visão Laser,Santos,Brazil;Universidade Metropolitana de Santos (UNIMES),Santos,Brazil;Faculdade de Ciências Médicas de Santos (UNILUS),Santos,Brazil, 5Hospital Oftalmológico Visão Laser,Santos,Brazil;Department of Ophthalmology and Visual Sciences,Universidade Federal de São Paulo (EPM/UNIFESP),São Paulo,Brazil;Faculdade de Ciências Médicas de Santos (UNILUS),Santos,Brazil
Purpose
This study aims to comparatively evaluate the morphological changes of the cornea after phacoemulsification (PHACO) and femtosecond laser-assisted cataract surgery (FLACS) without intercurrences in patients with type 2 diabetes mellitus.
Setting
Department of ophthalmology at the Hospital Oftalmológico Visão Laser in Santos - SP, Brazil.
Methods
A total of 95 diabetic patients with moderate cataracts (N2+ and N3+), 47 undergoing PHACO and 48 undergoing FLACS, were selected randomly for the study. Surgeries were performed by a single surgeon between July 2021 and December 2021. Cumulative dissipated energy (CDE) and total balanced saline solution (BSS) data were obtained at the end of each surgery. Changes in corneal endothelial cell density (ECD) and central corneal thickness (CCT) at three months postoperatively were investigated.
Results
After three months, evidence is lacking between groups in the CCT measures; the difference was neither statistically nor clinically relevant. However, for ECD, a significant and clinically significant difference was found; if all patients were treated with laser, the mean ECD would be 423.55 greater (RSE: 86.09; p-value < 0.001; 95% CI: 254.81–592.29) than the ECD potential means of 1656.423 among the conventional group (RSE: 74.90; p-value < 0.001; 95% CI: 1509.62–1803.23).
Conclusions
Diabetic patients under treatment with moderate cataracts may predispose themselves to a more significant loss of endothelial cells after conventional phacoemulsification than femtosecond laser-assisted cataract surgery.