ESCRS - PO0291 - Structural And Functional Outcomes Of An Advanced Monofocal Intraocular Lens Based On Spherical Aberration Modulation

Structural And Functional Outcomes Of An Advanced Monofocal Intraocular Lens Based On Spherical Aberration Modulation

Published 2023 - 41st Congress of the ESCRS

Reference: PO0291 | Type: Free paper | DOI: 10.82333/84g2-4036

Authors: Rosa Giglio* 1 , Alberto Grotto 1 , Riccardo Leonelli 1 , Serena Milan 1 , Marianna Presotto 1 , Elena Verdimonti 1 , Alex Lucia Vinciguerra 1 , Gianluca Turco 2 , Daniele Tognetto 1

1Department of Medical, Surgical and Health Sciences,University Eye Clinic of Trieste,Trieste,Italy, 2Department of Medical, Surgical and Health Sciences,University of Trieste,Trieste,Italy

Purpose

Evaluation of the surface profile and functional results of a new generation monofocal lens based on spherical aberration modulation (EVOLUX, SIFI) and comparison with a standard monofocal aspheric intraocular lens (IOL) (ZCB00, Johnson & Johnson) and with a monofocal plus refractive IOL (ICB00, Johnson & Johnson).

Setting

University Eye Clinic of Trieste, Trieste, Italy

Methods

Patients were divided into three groups: EVOLUX (Group 1), ZCB00 (Group 2), ICB00 (Group 3). Data were collected 1 month after implantation and included monocular visual acuity (corrected and uncorrected) for far (4 m) and intermediate (66 cm) distance and monocular defocus curves (from +1 to -3, 0.5 D steps). The primary endpoint was the assessment of uncorrected intermediate distance visual acuity (UIVA).

Scanning electron microscopy (Quanta250 SEM) was used to evaluate the optics profile of the IOLs under study.

Results

No statistically significant differences were observed for far visual acuity (both uncorrected and best corrected) among the 3 groups.

UIVA and IVA with correction for far (DCIVA) showed no statistically significant differences when comparing group 1 and 3.

UIVA and DCIVA values were significantly higher both in group 1 and 3 when compared to group 2.

The same trends were confirmed by defocus curves.

From structural analysis no diffractive profile neither zones wear detected by SEM analysis.

Conclusions

The new spherical aberration based monofocal IOL showed far vision outcomes comparable to a standard monofocal IOL with an increased performance at intermediate distance comparable to a refractive monofocal plus IOL.