ESCRS - PO0281 - A Scoping Review On The Placement Of Enhanced Monofocal Between Conventional And Extended Depth Of Focus Intraocular Lenses

A Scoping Review On The Placement Of Enhanced Monofocal Between Conventional And Extended Depth Of Focus Intraocular Lenses

Published 2023 - 41st Congress of the ESCRS

Reference: PO0281 | Type: Free paper | DOI: 10.82333/00z6-nn79

Authors: Joaquín Fernández* 1 , Carlos Rocha-de-Lossada 2 , Francisco Zamorano-Martín 3 , Marina Rodríguez-Calvo-de-Mora 4 , Manuel Rodríguez-Vallejo 1

1Ophthalmology Department, VITHAS Almería Hospital,Qvision,Almería,Spain, 2Ophthalmology Department, VITHAS Almería Hospital,Qvision,Almería,Spain;Ophthalmology Department,VITHAS Málaga,Málaga,Spain;Ophthalmology Department,Hospital Regional Universitario de Málaga,Málaga,Spain;Departamento de Cirugía, Área de Oftalmología,Universidad de Sevilla,Sevilla,Spain, 3Ophthalmology Department,Instituto de Oftalmología Conde de Valenciana,Ciudad de Mexico,Mexico, 4Ophthalmology Department, VITHAS Almería Hospital,Qvision,Almería,Spain;Ophthalmology Department,VITHAS Málaga,Málaga,Spain;Ophthalmology Department,Hospital Regional Universitario de Málaga,Málaga,Spain

Purpose

The aim of this review was to summarize the outcomes provided by mono-EDOF IOLs and to determine which of the endpoints described by the American National Standard (ANSI) for EDoF IOLs are met.

Setting

Qvision. Ophthalmology Department. VITHAS Almería Hospital

Methods

The MEDLINE, EMBASE, and WEB OF SCIENCE databases were searched, and the studies were screened for inclusion and data extraction by two independent reviewers. The search strategy was not limited by language but was restricted to studies published between 2020 and 2022. A narrative summary with tables was presented in accordance with the objectives of this scoping review. Compliance with the clinical outcome endpoints described in the American National Standard Z80.35-2018 (ANSI) for EDoF lenses was verified, and additional endpoints were defined.

Results

13 laboratory, 21 clinical, and 2 mixed studies were included, along with 2 systematic reviews. The mono-EDoF with the highest volume of evidence to date was Tecnis Eyhance. Although other IOLs were included in the laboratory studies, clinical evidence for them is still scarce, with only 1 study of IsoPure compared to a standard monofocal. Evidence in comparison to EDoF lenses is also scarce, even for Tecnis Eyhance, with only 3 studies including this lens in comparison to an EDoF. After the evaluation of the ANSI criteria, it was found that the failure for the increase in DoF >= 0.5 D for a visual acuity (VA) level of 0.2 logMAR, and none of the studies supported that the median monocular VA at an intermediate of at least 0.2 logMAR.

Conclusions

Other mono-EDOF IOLs beyond Tecnis Eyhance require additional clinical evidence. Until a standard classification is established, mono-EDOF lenses should still be classified as monofocal because they did not fully meet the ANSI standards.