ESCRS - PO0251 - Uveitis-Glaucoma-Hyphema (Ugh) Syndrome (A Case Report)

Uveitis-Glaucoma-Hyphema (Ugh) Syndrome (A Case Report)

Published 2023 - 41st Congress of the ESCRS

Reference: PO0251 | DOI: 10.82333/m14n-4898

Authors: Beatriz García Checa* 1 , Francisco Manuel Hermoso Fernandez 1 , Rocio Mora Romero 1 , Jose Antonio Vilchez Gonzalez 1 , Carmen Vera Bailón 1 , Blanca Revelles Peñas 1

1Ophthalmology,Hospital Universitario Clínico San Cecilio,Granada,Spain

To identify the underlying causes and signs of UGH Syndrome. Factors that have to be taken into consideration. 

Department of Ophthalmology of the San Cecilio University Hospital of Granada, Spain.

Observational case report. We used the PubMed database to find other prospective or retrospective studies.

63-year-old woman, pseudophakic for 8 years, who had recurrent episodes of blurred vision, floaters, redness, elevated intraocular pressure (IOP), vitreous hemorrhage and pain in the left eye. The puncture of aqueous humor was negative for herpes virus. Examination revealed depigmentation and atrophy of the iris (possibly due to the touch of the lens haptic), tyndall test (+++), blood deposit in endothelium and IOP was 36 mmHg. The patient underwent intraocular lens (IOL) explantation surgery (the superior lens haptic was out of the capsule), capsule extraction and anterior vitrectomy. There was no lens implantation due to the high myopia of the patient. After intervention, BCVA was 1, IOP was 18 and without inflammation signs.

To be aware of the mechanisms of uveitis-glaucoma-hyphema(UGH) syndrome:

  • Mechanical irritation caused by IOL malposition or subluxation provoking mechanical and repetitive trauma to the iris
  • IOL well positioned with proximity of the edge of the optic IOL edge to the lower pupillary margin, pressing on the peripheral iris.
  • Zonal laxity due to pseudoexfoliation caused by phacodonesis.
  • Previously rotated iris, plateau iris and fibrosis configuration capsule around the optics caused by contact at various points.