Evaluation Of Pericardium Patch Graft Thickness In Patients With Ahmed Glaucoma Valve Implantation: An Anterior Segment Oct Study
Published 2023 - 41st Congress of the ESCRS
Reference: PO0241 | Type: Free paper | DOI: 10.82333/jvfa-qd58
Authors: Yusuf Berk Akbaş* 1 , Nese Alagoz 2 , Cem Sari 2 , Cigdem Altan 2 , Tekin Yasar 2
1Ophthalmology,Basaksehir Cam and Sakura City Hospital,Istanbul,Türkiye, 2Ophthalmology,Beyoglu eye training and research hospital,Istanbul,Türkiye
Purpose
To evaluate prospectively the thickness change in tissues overlying the silicon tube of Ahmed Glaucoma Valve (AGV) in patients with an AGV implant and pericardium patch graft (PPG).
Setting
Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
Methods
This prospective study included participants who had been diagnosed with refractory glaucoma and underwent AGV implantation with PPG coverage between January 2020 and January 2021. Conjunctival epithelium, stroma and PPG thickness above the tube and peripheral region were measured by anterior segment optical coherence tomography (AS-OCT). For the standardization of the measurements, the central region was defined as the AS-OCT image section 4 mm from the limbus. And the peripheral region was defined as 1.5 mm temporal to the central region at the same AS-OCT image section. These measurements were obtained at 1, 6 and 12 months.
Results
Twenty-seven eyes of 27 patients were included in the study. The mean age of the patients was 39.84±12.9 years and most of the patients (77.7%) were diagnosed with secondary glaucoma. The PPG thickness decreased significantly both centrally (from 225.0 ± 61.6 mm to 115.6 ± 47.2 mm, P<0.001), and peripherally (from 349.5 ± 60.3 mm to 319.9 ± 55.8 mm, P<0.001). Likewise, the total thickness including all layers decreased significantly both centrally (from 422.3 ± 111.2 mm to 258.6 ± 89.4 mm, P<0.001), and peripherally (from 690.9 ± 132.7 mm to 613.7 ± 115.4 mm, P<0.001). At 12 months, two eyes (7.4%) had a total thickness of <100 mm and nine eyes (33.3%) of <200mm. Exposure was not observed in any patients throughout the follow-up.
Conclusions
AS-OCT is a non-contact and non-invasive method which was found useful in evaluating PPG thickness quantitatively. The mean thickness of PPG decreased progressively throughout the 12 months follow-up period both in central and peripheral regions. These patients should have a lifelong follow up to detect the exposure. These findings could be useful to understand the course of exposure.