Analysis Of Angle Parameters Using Swept-Source Oct (Casia2) In Aged Population In South Korea

To analayze angle parameters using Swept-source OCT (CASIA2) in aged population in South Korea 

A total of 457 eyes belonging to 264 individuals who had their angle parameter measured using CASIA2 between November 2021 and October 2022 as a preoperative investigation for upcoming cataract surgery at department of Ophthalmology in Seoul National University Hospital were recruited.

The measured angle parameters using CASIA2 include Anterior Chamber Depth (ACD), Anterior Chamber Width (ACW), Lens Vault (LV), Angle Opening Distance (AOD), Angle Recession Area (ARA), and Trabecular Iris Angle (TIA). Pearson's correlation coefficient test and multiple regression analysis were conducted to investigate the relationship between the angle parameters and non-ocular parameters such as age, gender, height, weight and body mass index (BMI).

In South Korean population with a mean age of 72 years, mean±SD values of ACD, ACW and LV were 2.54±0.45mm, 11.33±0.50mm and 0.426±0.33mm respectively. The temporal and nasal measurement of AOD, ARA and TIA taken at 500 and 750 um from scleral spur were also recorded. The Pearson’s correlation test showed that angle parameters were well correlated with age and height (P <0.05 in 13/15 parameters), partially and poorly correlated with weight, gender and BMI (P <0.05 in 7/15, 1/15 and 0/15 parameters respectively). In multiple regression analysis, no formula using non-ocular parameters were able to suggest prediction model of any angle parameters more than 9% (adjusted R-squared <0.09). 

Our study describes angle parameters of aged South Korean population using CASIA2 (SS-OCT). Angle parameters were generally correlated with age and height, but not with gender, weight and BMI. The prediction model for angle parameters derived from non-ocular parameters had an explanatory power of less than 9%.