Corneal Decompensation After Reactivation Of Cytomegalovirus After Covid 19 Vaccine

To describe three cases of corneal decompensation after reactivation of cytomegalovirus after the COVID 19 vaccine.

The cases of three patients referred from other centers to the

Carlos Andrade Marin Hospital (Quito - Ecuador).

Case 1: 65-year-old patient with a history of a booster vaccine against COVID 19 a month ago who presented corneal decompensation due to endothelial failure in the right eye

Case 2: 75-year-old patient with a history of the first dose of vaccine against COVID 19 who presented symptoms of endothelitis in the right eye that led to corneal decompensation of poor evolution.

Case 3: 84-year-old patient with a history of the second dose of vaccine against COVID 19 who presented bilateral corneal decompensation two months after the application of the vaccine.

Antibodies for Cytomegalovirus and Herpes were obtained in all cases, the IGG being positive for Cytomegalovirus, none of them had a history of ocular surgery or another cause for corneal decompensation. Three patients underwent Penetrating Keratoplasty with good outcomes

Cytomegalovirus viral infections can be reactivated by vaccination for COVID 19 and trigger corneal decompensation in patients.