Overall Visual Outcomes From A Real-World Study Of Presbyopia-Correcting Iols In A Large Population

To present real-world visual and patient-reported outcomes in a large cohort of patients bilaterally implanted with the AcrySof IQ Vivity presbyopia-correcting IOL.

Multicenter, ambispective registry study conducted in Europe, Australia and New Zealand evaluating the performance of bilaterally implanted AcrySof IQ Vivity and AcrySof IQ Vivity Toric IOLs in a real-world setting through routine clinical practice. This cohort includes 4% post-corneal refractive surgery subjects and 28% with associated ocular comorbidities. 

At 3-6 months post-op, following second eye surgery per local clinical practice standards, subjects bilaterally implanted with the AcrySof IQ Vivity and/or Vivity Toric IOL underwent visual performance assessments. Binocular uncorrected and corrected visual acuity was assessed at distance, intermediate (66 cm) and near (40 cm) (UCDVA/BCDVA, UCIVA/DCIVA and UCNVA/DCNVA). Patient satisfaction and spectacle independence were assessed with validated questionnaires, using the Catquest-9SF and IOLSAT, respectively. Patient reports of visual disturbance were also assessed.

910 subjects were available for analysis. The mean age was 67.1 ± 9.3 years. Binocular mean UCDVA was 0.01 ± 0.10 logMAR, UCIVA was 0.08 ± 0.12 logMAR, and UCNVA was 0.25 ± 0.15 logMAR. Mean MRSE (first eye) was -0.19 ± 0.39 D (23.7% had mini-monovision). Most subjects (91.4%) reported being satisfied with their vision; 79.2% had no difficulty with vision doing a hobby of interest. The percentage of subjects reporting never/rarely needing to wear glasses to see up close was 60.2%, at arm’s length 89.2%, and far away 93.4%. The percentage of subjects reporting “none” for seeing halos was 91.5%, for glare 91.6%, and for starbursts 94.6%. Posterior capsulotomy had been required in 4.8% of subjects at 12 months. 

In this real-world study in a diverse large population of subjects bilaterally implanted with the AcrySof IQ Vivity presbyopia-correcting IOL, we have demonstrated excellent distance (20/20), intermediate (~20/25), and functional near (~20/32) visual acuity. In general, subjects were spectacle independent for distance to intermediate, reported high visual satisfaction with little or no difficulty in performing daily activities and very little visual disturbances.