The Influence Of Iris -Ciliary Angle (Ica) On The Clinical Vault After Implantation Of V4c Implantable Collamer Lens: A Chain Mediation Model Of Icl Haptic Related Factors

This study aims to identify the relationship between iris -ciliary angle (ICA) and the clinical vault. Additionally, we also seek to investigate the chain mediating effects of the ICL haptic related factors on this relationship.

Hongshan Aier Eye Hospital, Wuhan, China

The participants were categorized into three groups according to the ICA value as follows: low ICA group (＜35°) ;moderate ICA group (35°-70°);high ICA group （＞70°）.We compared the preoperative ocular characteristics and postoperative examinations among the three groups. Multivariate linear regression was performed to evaluate the relationship between clinical vault and preoperative ocular parameters. The Process V4.0 in SPSS and Hayes’s PROCESS model 6 was conducted to further elucidate the mediating effects of the final tip point of ICL haptic and the ICL arc-Lens arc on the relationship between the ICA and clinical vault.

There was a significant difference in the positions of the ICL haptic among three ICA groups. The sex、Lens thickness(LT)、ICA、crystalline lens rise and the implanted ICL Size were the factors significantly associated with clinical vault in the Multivariate linear regression analyses. A significant negative correlation was found between the ICA and clinical vault (p＜0.01).The chain mediation model revealed that the final tip point of ICL haptic and the ICL arc-Lens arc were sequential mediators between ICA and clinical vault (effect = -1.63, 95% CI = -2.72 to -0.73).

The ICA was associated with clinical vault via the mediation effect of

the final tip point of the ICL haptic and the ICL arc -lens arc. Assessment of

ICL haptic related parameters adds significant information to interpret the clinical vault after surgery.