Implantable Collamer Lens On Thin Cornea Versus Smile In Refraction-Matched Low-Moderate Myopia: A Prospective Non-Inferiority Study
Published 2023 - 41st Congress of the ESCRS
Reference: FP03.04 | Type: Free paper | DOI: 10.82333/j4jy-wz61
Authors: Kangjun Li* 1 , Zheng Wang 2 , Ming X Wang 3
1AIER EYE Group,Xi"An,China, 2AIER EYE Group,Guangzhou,China, 3AIER EYE Group,Nashville,United States
Purpose
To compare the safety, efficacy and vision quality of implantable collamer lens (ICL) implantation in low to moderate myopia with thin cornea, versus that in similar myopia range eyes that have undergone small incision lenticule extraction (SMILE).
Setting
A Prospective Non-Inferiority Study
Methods
This prospective study screened patients scheduled for refractive surgery with thin corneas (central corneal thickness [CCT] < 480 μm) who have received ICL or Toric ICL(TICL) and those with normal CCT (≥ 480 μm) as controls undergone SMILE. One-to-one matching was performed by preoperative manifest refraction spherical equivalent (SE), age, and pupil size. Routine examinations, including visual acuity, refraction and higher-order aberrations (HOAs) were performed to all patients at baseline and 1 year.
Results
The recruited patients with no difference in SE between ICL/TICL and SMILE group (-4.34 ± 1.21 diopters[D] vs -4.37 ± 1.17 D; P = .98), but with significant difference in CCT (452.23 ± 21.78 vs 527.24 ± 28.43; P < .001). At 1 year, thin cornea patients was similar to control group in terms of efficacy index (1.16 ± 0.25 vs 1.15 ± 0.23; P = .66), safety index (1.14 ± 0.22 vs 1.12 ± 0.24; P = .88), predictability (92% vs 95% ±0.5D of attempted correction SE; P = .62), and total ocular HOAs(0.17 ± 0.01 vs 0.16 ± 0.05; P = .17).
Conclusions
This prospective refraction-matched study suggest that ICL/TICL produced promising refractive outcomes on thin cornea eyes, which suggesting that it may be an alternative surgical option for such eyes.