Short-Term Effects On Fundus Blood Flow After Cataract Surgery With Different Fluid Perfusion Systems In High Myopia Patients

To investigate the changes of fundus blood flow in the early stage of phacoemulsification in cataract patients with high myopia under different fluid perfusion systems, and to further evaluate the effectiveness of Active Sentry main control handle (AS handle) combined with CENTURION® active fluid flow control technology in combined height Clinical value and application significance in cataract surgery for myopia.

For cataract patients with high myopia, there may be a state of low blood supply to the retinal optic nerve before cataract surgery, and the intraocular pressure increase caused by intraoperative high perfusion pressure will aggravate the retinal optic nerve ischemic damage in these patients. Adjustment of  fluid systems is expected to reduce retinal optic nerve damage caused by fluctuations in intraocular pressure, and increase the safety of cataract surgery in patients with high myopia.

Prospective trial. From Aug.2020 to Aug. 2022,60 eyes of patients over 40 years old who were diagnosed as "cataract with high myopia" who were going to undergo cataract surgery in our hospital were included. Control group:the gravity flow system was used, and the intraoperative bottle height was set to 95cmH2O;Observation group: the main control liquid flow system was used during the operation, and the intraoperative IOP was set to 70mmHg, and 30 patients were included in each group. Hemodynamic parameters before surgery, 2 hours、1 day and 1 week after surgery:Color ultrasound Doppler bulb、SFCT in OCT-EDI mode;measured by OCTA The vascular density of the SVP was observed, and the change trend of the two groups was observed.

For the hemodynamic parameters after color ultrasound Doppler bulb, the postoperative CRA-PSV in all groups decreased at 2 hours、1 day and 1 week after operation, and the fluctuation range of the control group was significantly higher than that of the observation group. The mean values ​​of SFCT at 2 hours、1 day and 1 week after operation in each group were thicker than those before operation, but the difference was not statistically significant. The density of SVP blood vessels in both groups decreased 2 hours and 1 day after operation compared with that before operation, and basically recovered to pre-operation 1 week after operation, and the control group was significantly lower, and the difference was statistically significant .

Active liquid flow control technology has important clinical value and application significance in cataract surgery with high myopia. And it can effectively reduce the impact of surgery on eye blood flow.