PRELIMINARY RESULTS OBTAINED WITH THE NEW SOFTWARE DEVELOPED FOR THE VEMOS EUROPEAN PROJECT (VIRTUAL EYE MODEL SYSTEM FOR PERSONALIZED REFRACTIVE SURGERY TREATMENT).

The aim of this study was to evaluate the precision of the new software developed which consists of a virtual representation of the patient´s eye based on real eye data obtained from the topographer VEMoS-AXL and IOL Master 700. This software, based on the optical physics of the eye, not only simulates visual quality of the patient but also serves as a portal for the data collection of the clinical trial. Validation of this European project has been achieved through the comparison of the results obtained from the Zernike coefficients and metrics given by the developed software and a commercial optical simulation software (Zemax, Radiant Zemax LLC).

In order to build the personalized virtual eye of the patient, biometric data has been extracted from the eye examinations performed with the VEMoS-AXL (CSO) and IOL Master 700 (Zeiss). Algorithms are specifically designed to represent raytracing and the effect light rays have when crossing the different surfaces of the eye. As a result, different parameters, metrics and graphs are provided for medical evaluation and support in decision-making. Bearing in mind that visual acuity is mainly determined by the Zernike coefficients and metrics of each patients’ eye, these values have been compared with those obtained with the Zemax software. Simulations with the software are also being performed to further enhance the verification of the newly developed software for the VEMoS European project. Two cases have been randomly selected from the recruited group in order to be able to preliminarily evaluate the functioning of the software.

From the software developed, Zernike coefficients are obtained. They are then compared with Zemax for a ray tracing in backwards mode. Considering the coefficient related to blur as a reference, an error of 0.004 μm is presented for case 1 and an error of 0.002 μm for case 2, between the analysis done with Zemax and the VEMoS software. For those related to astigmatism, an absolute error of 0 μm is presented for case 1 and of 0.001 μm for case 2. The general absolute error for the most influential coefficients obtained have a magnitude between 0 and 0.012 μm. The same comparison is done for the sphere, cylinder and angle values, also presenting similar results. Case 1 had a sphere of -7D and cylinder of -1.75D for an angle of 180º given by optometric examinations whereas the software gave a sphere of -6.036D and a cylinder of -1.244D for an angle of 166º

The VEMoS software developed manages to obtain results of Zernike coefficients and values of the sphere, cylinder and angle which are similar to those results obtained with the Zemax software and the optometric examinations carried out. To further verify these results, other cases have been compared and the simulations obtained can be seen in the app interface designed specifically for the VEMoS project. These simulations will then be contrasted with the graphics obtained by the VEMoS-AXL device