ESCRS - P151 - OCULAR CHANGES IN PATIENTS WITH SYSTEMIC SCLEROSIS

OCULAR CHANGES IN PATIENTS WITH SYSTEMIC SCLEROSIS

Published 2023 - 27th ESCRS Winter Meeting

Reference: P151 | Type: Presented Poster & Poster Submission | DOI: 10.82333/mr0c-0f28

Authors: Małgorzata Luboń* 1 , Wojciech Luboń 1 , Ewa Mrukwa-Kominek 1

1Department of Ophthalmology,Prof Gibinski's Univesity Clinical Center, Medical University of Silesia,Katowice,Poland;Department of Ophthalmology,Faculty of Medical Sciences in Katowice, Medical University of Silesia,Katowice,Poland

Purpose

Systemic sclerosis (SSc) is a rare, chronic autoimmune disease with unknown etiology. Its prominent features are fibrosis, vasculopathy and impaired immune response. Disease can also affect eyes leading to various findings in ophthalmological examination. Aim of this study was to determine the prevalence and type of ocular involvement in patients with SSc.

Setting

Department of Ophthalmology of University Clinical Centre in Katowice.

Methods

A systematic literature review was conducted using electronic databases. A combination of following keywords was used: “systemic sclerosis” and ophthalmology-related search terms, including the keywords “eye”, “ocular” and “ophthalmic”.

Results

The most common ocular pathologies were eyelid changes like stiffness, tightness and telangiectasia diagnosed in 51,1- 77,0% of patients. Conjuctival involvement including neovascularisation, teleangiectasia, varicose even dilatation was seen in 15,7-63% of patients. 48,9-64,7% of patients presented cataract and 33,0- 50,0% of them had choroidal perfusion abnormalities. Retinal changes were seen in 10-34% of cases mainly as hard exudates and tortuosity of vessels.

Conclusion

The most common ocular complicatios in the course of SSc are eyelid, conjunctival, dry eye syndrome and choroidal perfusion disorders. They result from fibrosis and vasculopathy, which are the main features of the underlying disease. Ocular involvement occurs in many rheumatological diseases, hence clinicians should be vigilant not to miss the ophthalmological pathology in the course of SSc and ensure adequate treatment is provided at the appropriate time.