PERIPHERAL ULCERATIVE KERATITIS REVEALING AN ACUTE MYELOID LEUKEMIA:CASE REPORT
Published 2023
- 27th ESCRS Winter Meeting
Reference: P136
| Type: Presented Poster & Poster Submission
| DOI:
10.82333/tnm9-zb78
Authors:
Salma El Moataz Billah* 1
, Soukaina Homaide 1
, Adil Mchachi 1
, Leila Benhmidoune 1
, Ryad Rachid 1
, Mohammed El Belhadji 1
1Ophtalmology 20 Aout hospital,Laboratoires Théa,CASABLANCA,Morocco
Purpose
Peripheral ulcerative keratitis (PUK) is an inflammatory condition of the peripheral cornea characterized with epithelial defects and stromal destruction as a result of a complex interplay of factors including host autoimmunity and the peculiar anatomic and physiologic features of the peripheral cornea. PUK can be due to vasculitides ، collagen vascular disease and other systemic diseases. Systemic malignancies have been reported as rare associations of PUK.
Setting
Ophtalmology departement , 20 Aout 1953 teaching hospital of casablanca, Morocco.
Methods
We report the case of a patient with acute myeloid leukemia revealed with a peripharal ulcerative keratitis.
Results
A 45 year-old female patient with no medical history presented to the emergency department with complaints of pain, redness, and photophobia in the left eye evolving for 2 weeks along with progressive decrease of vision. Examination of the left eye revealed a PUK and localized scleritis. Dilated fundus examination revealed numerous white centered hemorrhages corresponding to Roth spots. At physical examination, a general cutaneous and mucosa pallor was noted. An urgent full blood count revealed pancytopenia. Bone marrow examination was consistent with acute myeloid leukemia diagnosis. The patient received systemic steroids with adjuvant therapy and was referred to the hematology departement for the management of leukemia.
Conclusion
This case highligths that beside infective or autoimmune causes, life-threatening systemic
malignancies should be thouroughly evaluated while investigating PUK etiology.