BILATERAL KEYSER FLEISCHER RING IN WILSON DISEASE

Published 2023 - 27th ESCRS Winter Meeting

Reference: P134 | Type: Presented Poster & Poster Submission | DOI: 10.82333/pb32-vc55

Authors: Taha Boutaj* ¹ , Salma Moutamani ¹ , Hamza Lazaar ² , Romaissae Benkirane ² , Latifa Sbai ² , Samira Tachfouti ² , Abdellah Amazouzi ² , Ouafa Cherkaoui ²

¹Hôpital des spécialités,Rabat,Morocco, ²Ophthalmology A,Hôpital des spécialités,Rabat,Morocco

Purpose

To report the case of a 36-year-old patient with a history of Wilson's disease who presented a bilateral Kayser-

Fleischer ring.

Setting

Department of Ophthalmology A. Hopital des specialites. Rabat. Morocco

Methods

We report the case of a 36-year-old male patient, from a consanguineous marriage, with a history of Wilson's

disease in its three clinical forms, hepatic, neurological and psychiatric.

Results

Visual Acuity was 7/10 in both eyes. Intraocular pressure was normal. Examination of eyelid found a meibomite.

Bio-microscopic examination objectives a bilateral Keyser Fleischer ring. The anterior chamber was normal. After dilation,

the examination of the lens is normal. The fundus was unremarkable. The biological assessment shows a low blood level

of ceruloplasmin at 10 mg/dl and a high 24-hour cupruria at 126 micrograms. Brain MRI reveals generalized signal

change, gliosis, and atrophy of the thalamus and brainstem.

Conclusion

Wilson disease is a rare, autosomal recessive disorder caused by abnormal copper accumulation in the

body particularly involving the brain, liver, and cornea. Ophthalmologic manifestations are one of the criteria used to

establish a provisional diagnosis of Wilson's disease. It can be treated and managed if it is diagnosed early.