OCULAR GREFT VERSUS HOST DISEASE IN PEDIATRIC BONE MARROW TRANSPLANTATION PATIENTS
Published 2023 - 27th ESCRS Winter Meeting
Reference: P132 | Type: Presented Poster & Poster Submission | DOI: 10.82333/17wh-wf77
Authors: betul akcay* 1 , mert avcu 1
1umraniye research and education hospital,istanbul,Türkiye
Purpose
To evaluate of dry eye associated with ocular graft-versus-host disease (GVHD) in pediatric hematopoietic stem cell transplantation patients.
Setting
umraniye research and training hpspital
Methods
Retrospectively the records of pediatric patients with ocular GVHD were evaluated and ophthalmologic examination findings as well as Schirmer test results, invasive and noninvasive tear film break-up time, and corneal staining grades and meibomiography findings were recorded. Additionaly ocular tretment ,systemic treatment , involvement of other systems and additional interventions were also evaluated.
Results
Ocular GVHD was detected in 9 ( 18%) of 50 patients. Four patients had grade 1 skin invovement , 1 has grade 2 skin involvement , 1 has grade 3 skin and liver involvement . All patients received artificial tears and cyclosporin treatment , punctal plug applied to two patients .
Conclusion
In children, chronic ocular GVHD is a common finding of GVHD after HSCT. Therefore, these patients should be examined periodically for dry eye.