ESCRS - P111 - AMEBIC KERATITIS : ABOUT 5 CASES

AMEBIC KERATITIS : ABOUT 5 CASES

Published 2023 - 27th ESCRS Winter Meeting

Reference: P111 | Type: Free Paper Submission | DOI: 10.82333/ntwh-y775

Authors: Mohamed Amine Amine Krichene* 1 , Salma Hassina 1 , Rania Lakraa 1 , Khalil Mrad 1 , Louai Serghini 1 , Abdellah Elhassan 1 , Amina Berraho 1

1UH IBN SINA,rabat,Morocco

Purpose

 
Evaluate the clinical features in five patients diagnosed in our department.
Retrospective stuy of risk factors, clinical diagnosis and therapeutic characteristics 

 

Setting

Ophtalmology B departmet at IBN SINA universitary hospital , Rabat , Morocco

Methods

Our study was carried out on 5 cases that were confirmed by parasitological examination, and demographic data, affected eye, risk factors and time to diagnosis from the onset of symptomatology were collected.

Results

Three women and two men with a mean age of 38.5 years were admitted for corneal abscesses in three cases and for pseudodendritic keratitis in two cases. Two patients had a history of contact lens wear, two patients reported contamination by dirty water, and only one case revealed unrecognized diabetes. Corneal sampling allowed the isolation of Acanthamoeba type amoebae in 3 cases and in 2 cases the diagnosis was made by Polymerase Chain Reaction (PCR). All patients received a broad spectrum antibiotic treatment associated with hexamidine, ketoconazole was associated in 3 cases and PolyHexaMethylene Biguanide (PHMB) in 1 case. The evolution was marked by panophthalmia and phthisis of the globe in 1 case, corneal opacity with neovascularization in 2 cases requiring a corneal transplant. Regression with total recovery was noted in the 2 cases of epithelial keratitis.

Conclusion

Early diagnosis and treatment are essential to preserve visual acuity in the face of amoebic keratitis.