ESCRS - P005 - ANTERIOR SCLERAL THICKNESS IN HEALTHY EYES MEASURED USING SWEPT-SOURCE OCT

ANTERIOR SCLERAL THICKNESS IN HEALTHY EYES MEASURED USING SWEPT-SOURCE OCT

Published 2023 - 27th ESCRS Winter Meeting

Reference: P005 | Type: Presented Poster & Poster Submission | DOI: 10.82333/na50-zt73

Authors: Neus Burguera Giménez* 1 , Celeste Briceno-Lopez 1 , Amparo Díez-Ajenjo 2 , Mª José Luque-Cobija 1 , Mª Carmen García-Domene 1 , Noemi Burguera 3 , Cristina Peris-Martínez 4

1Cathedra Alcon-FISABIO-UVEG,Cornea and anterior segment unit, FISABIO Oftalmología Médica,Valencia,Spain;Department of Optics, Optometry and Vision Sciences,University of Valencia,Burjassot,Spain, 2Department of Optics, Optometry and Vision Sciences,University of Valencia,Burjassot,Spain;Cathedra Alcon-FISABIO-UVEG,Cornea and anterior segment unit, FISABIO Oftalmología Médica,Valencia,Spain, 3Ophthalmology department, Q vision,Vithas Virgen del Mar Hospital,Almería,Spain, 4Cathedra Alcon-FISABIO-UVEG,Cornea and anterior segment unit, FISABIO Oftalmología Médica,Valencia,Spain;Surgery Department, Ophthalmology,School of Medicine, University of Valencia,Valencia,Spain

Purpose

To asses anterior scleral thickness (AST) at several eccentricities and scleral regions in a healthy population using swept source-OCT.

Setting

Cathedra Alcon-FISABIO-UVEG

FISABIO Oftalmología Médica

University of Valencia

Methods

Cross-sectional and prospective study with 50 eyes of 50 healthy patients aged between 18 and 45 years recruited from FISABIO Ophthalmological Medical Centre and University of Valencia. All patients underwent a comprehensive ophthalmological exam including subjective refractive error, slit lamp biomicroscopy, axial length (AL) measurement with IOL Master 700 (Carl Zeiss Meditec, Jena, Germany), corneal analysis with Pentacam HR (Oculus Optikgeräte GmbH, Wetzlar, Germany) and intraocular pressure with Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany). The AST was analysed across four scleral zones (nasal, temporal, superior, and inferior meridian) at three scleral locations (1, 2, and 3-mm posterior to the scleral spur) using the Casia 2 (AS SS-OCT, Tomey, Japan). Only eyes with AL between 22 and 26 mm and spherical equivalent (SE) less than -6.00 D were included. A two-way repeated measures ANOVA was conducted to assess AST differences throughout scleral eccentricity, scleral region and to explore the interaction between eccentricity and region. A multivariate model was created to associate AST with several ocular parameters.

Results

The mean age was 29.02 ± 9.58 years. The mean SE error and AL were −1.04 ± 1.51 D and 23.74 ± 1.00 mm, respectively. AST was thickest in the inferior (581 ± 52 μm) and thinnest in the superior meridian (441 ± 42 μm) when compared to all meridians (p < 0.001), and similar in the nasal (529 ± 53 μm) and temporal (511 ± 59 μm) meridians (p > 0.05). The sclera exhibited the thinnest point 2 mm posterior to the scleral spur (p < 0.001) at all meridians. Both factors, scleral eccentricity (p= 0.044, ηp2= 0.07) and scleral region (p= 0.0005, ηp2= 0.62), have significantly effect on AST. The AST was significantly linked with axial length, central corneal thickness, and intraocular pressure (p < 0.001).

Conclusion

Tissue thickness varied significantly among meridians supporting the hypothesis of the asymmetrical expansion of the ocular globe. The AST was associated with several factors as axial length, central corneal thickness and intraocular pressure.