ESCRS - O22 - OUTCOMES IN PHACO-DMEK VERSUS DMEK AND PHACO IN 2 TIMES WITH PREMIUM IOL

OUTCOMES IN PHACO-DMEK VERSUS DMEK AND PHACO IN 2 TIMES WITH PREMIUM IOL

Published 2023 - 27th ESCRS Winter Meeting

Reference: O22 | Type: Free Paper Submission | DOI: 10.82333/zgzs-0y52

Authors: Antonio Cano-Ortiz 1 , Álvaro Sánchez Ventosa* 1 , Alberto Villarrubia Cuadrado 1 , Timoteo González-Cruces 1

1hospital arruzafa,cordoba,Spain

Purpose

Objective: to study the refractive and visual results in patients with Fuchs dystrophy undergoing DMEK and cataract surgery with AcrySof IQ Vivity IOL implantation. 

Setting

Hospital Arruzafa, Cordoba , Spain

Methods

Prospective, descriptive, 3 months follow up, two-arm study. This prospective study was approved by the Ethics Committee of Córdoba (Spain) and was conducted in accordance with the tenets of the Declaration of Helsinki. Eyes with Fuchs dystrophy requiring endothelial transplant (DMEK) and candidates to Vivity IOL implantation were included in the study. The exclusion criteria considered were any other ocular pathology apart from cataract and Fuchs endothelial dystrophy and corneal thickness higher than 700µm. 30 eyes were considered for the study, and it is an interim analysis with 7 eyes of 7 patients. Outcomes of the study will be updated.

Results

Results:

Group 1 and 2 have a BCDVA (decimal scale), of 0.96 (0.22) and 0.87 (0.14), not being statistically significant differences at 1 month.At 3 months,BCDVA (decimal scale), was 1.02 (0.12) and 0.82 (0.17), for groups 1 and 2 respectively, with no statistical differences between them.There were no significant differences in sphere and cylinder at 1 or 3 months after cataract surgery.Endothelial cellularity one and 3 months after cataract surgery was 1.512 and 1.474 cells/mm2 in group 1 and 2.284 and 1.859 in group 2, being close to significance (p=0.06). 

Conclusion

Conclusions: 

The results in the overall population (7 eyes) show the safety (BCVA) of Vivity implantation in this cohort of patients.

We have not found significant differences in refractive results in DMEK surgery associated with phaco in the same act versus DMEK first and phaco three months later.

Endothelial cellularity was lower in the group where phaco was performed 3 months after DMEK without significant differences.

Studies with a larger sample size are needed to be able to establish differences between both approaches.

Funding: This study was supported by an investigator-initiated study grant from Alcon Healthcare (IIT#67061475).