REGENERATIVE CAPACITY OF INTRACAMERAL PRP FOR PSEUDOPHAKIC BULLOUS KERATOPATHY

Published 2023 - 27th ESCRS Winter Meeting

Reference: CR38 | Type: Case Report (Cornea Day) | DOI: 10.82333/9d86-xg38

Authors: Anita Syla Lokaj* ¹ , Faruk Semiz ¹ , Njomza Hima Musa ¹ , Ceren Ece Semiz ¹ , Gokce Idil Semiz ¹ , Olcay Semiz ¹ , Zekerya Alp Demirsoy ¹

¹Ophthalmology,Eye Hospital,Prishtine,Albania

Purpose

To present successful management of moderative corneal edema following cataract surgery by using

intracameral injection of eye platelet-rich plasma (E-PRP) in a case of pseudophakic bullous

keratopathy

Setting

Eye Hospital,Department of Ophthalmology,Prishtinë,Kosova

Report of case

A 60-year-old-male presented to the our clinic with diminution of vision in the left eye for 3 months which was associated with intermittent photophobia and colored haloes around lights, especially on waking up in the morning. The patient did cataract surgery 3months before.We use AS-OCT, Slit lamp and Corneal pachymetry that showing multiple small sub-epithelial micro and macro bullae involving whole cornea,diffuse stromal edema and mild Descemet’s membrane thickening with folds. We give 0.5 ml of e-PRP intracameral in sterile condition.

Different medical treatment using a lot of drops have failed. A sterile 0.5 mL of E-PRP

was injected into the anterior chamber. Clinical and anatomical improvement began from the

first week, and corneal edema totally resolved at 2 months. Postoperatively, no significant

side effect was noted. We followed by Slit lamp,Anterior segment-OCT and Corneal Pachymetry

that thEy showed improvement of corneal trnsaparence and total disappearance of fluid in the

cystic superficial epithelium. . The patient is in follow-up procedure.

Conclusion / Take home message

It can be concluded from thIS studY that the therapeutic response withi intracameral injection of PRP was actually satisfactory in moderate pseduphakic bullous keratopathy.In this case, intraocular E-PRP was a promising, apparently safe, and effective treatment option in management of bullous keratopathy, in which conventional approaches failed.