ESCRS - PP23.07 - Systemic And Psychological Comorbidities Of Dry Eye Disease In Adult Korean Population

Systemic And Psychological Comorbidities Of Dry Eye Disease In Adult Korean Population

Published 2022 - 40th Congress of the ESCRS

Reference: PP23.07 | Type: ESCRS 2022 - Posters | DOI: 10.82333/ysep-9z40

Authors: Sang Beom Han* 1 , Hee Kyung Yang 2 , Joon Young Hyon 3

1Ophthalmology,Kangwon National University Hospital,Chuncheon,Korea, Republic Of, 2Ophthalmology,Seoul National University,Seongnam,Korea, Republic Of, 3Seoul National University,Seongnam,Korea, Republic Of

Purpose

To evaluate the association between dry eye disease (DED) and various systemic and psychological diseases in adult Korean population

Setting

Population-based cross-sectional data using the Korea National Health and Nutrition Examination Survey 20017-2018 (KNHANES VII) was used.

Methods

This study includes 6,732 participants aged 40 years or older. Data including the presence of DED, demographic variables including age, sex, residential area (rural or urban), education level, occupation and household income level, lifestyle factors, such as, smoking and physical activity, psychological conditions including perceived stress and depression, systemic diseases, such as, hypertension, diabetes mellitus, hyperlipidemia, obesity, cerebral stroke, ischemic heart disease, arthritis, osteoporosis, asthma, thyroid disease, liver cirrhosis, chronic renal failure, stomach cancer, colon cancer, lung cancer and thyroid cancer were evaluated for the prevalence and risk factors of DED using the KNHANES VII data. 

Results

Prevalence of DED was 12.1% (95% confidence interval (CI), 10.8 - 13.4). In multivariate analysis, female sex and residing in urban area were associated with increased risk of DED. Patients of 70 years or older showed decreased risk of DED compared to those of 40 to 69 year of age. Psychological conditions, such as, perceived stress and depression, and systemic conditions, such as, ischemic heart disease, angina, chronic renal failure, degenerative arthritis, osteoarthritis and rheumatoid arthritis were associated with the increased risk of DED.

Conclusions

The prevalence of DED in Korean adult population of 40 years or older was high. DED can be associated with several psychologic conditions and systemic diseases.