Comparison Of Clinical And Patient-Reported Outcomes Of A Standard Monofocal And A New Monofocal Intraocular Lens With Modified Optical Profile

To evaluate and compare the clinical outcomes and patient-reported outcomes (PROMs) obtained after cataract surgery with a conventional monofocal IOL and an enhanced monofocal intraocular lens (IOL) with a modified optical profile

¹Department of Ophthalmology, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands

²Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain

Randomised clinical trial enrolling 70 patients (age, 52-87 years) undergoing cataract surgery. Two group were created according to the type of IOL implanted: Vivinex iSert from Hoya Surgical Optics (Vivinex group, 35 patients) and Tecnis Eyhance ICB00 from Johnson & Johnson Vision (Eyhance group, 35 patients). Uncorrected (UDVA) and corrected distance visual acuity (CDVA), uncorrected (UIVA) and distance-corrected intermediate visual acuity (DCIVA), refraction, and self-perceived visual function (Catquest-9SF) were evaluated during a 3-month follow-up

No significant differences were found between IOL groups in UDVA and CDVA (p≥0.093). In contrast, monocular and binocular UIVA and DCIVA were significantly better in the Eyhance group at 1 (p≤0.015) and 3 months postoperatively (p≤0.002). Postoperative DCIVA was 20/25 or better in 71.4% and 20.0% of patients in Eyhance and Vivinex groups, respectively. Rasch calibrated Catquest scores were somewhat higher in the Eyhance group compared to Vivinex group, but differences did not reach statistical significance (p≥0.102). However, only in the Eyhance group, significant correlations were found between the change in UIVA and in Catquest scores (-0.365≤r≤-0.444, p≤0.032).

The enhanced monofocal IOL evaluated provides better intermediate visual function in comparison with a standard aspheric monofocal IOL, which is in relation with an improvement in the self-perceived level of vision achieved after surgery according to the patient