5-Year Clinical Effectiveness Of Ab-Interno Canaloplasty In Reducing The Medication Burden In Glaucoma Patients
Published 2022 - 40th Congress of the ESCRS
Reference: PP15.04 | Type: Free paper | DOI: 10.82333/qyk9-j543
Authors: Norbert Koerber* 1 , Simon Ondrejka 1
1Augencentrum Köln,Köln,Germany
Purpose
To investigate the clinical effectiveness of ab-interno canaloplasty (iTrack, Nova Eye, Inc., Fremont, USA) with or without phacoemulsification in reducing the number of medications in patients with primary open-angle glaucoma (POAG).
Setting
Augencentrum Köln-Porz, Köln, Germany
Methods
This retrospective single-center case series recruited patients with POAG who had undergone canaloplasty using the iTrack microcatheter via an ab-interno surgical technique (ABiC) with or without phacoemulsification. Patients were divided into 5 groups according to the baseline number of medications (0, 1, 2, 3, 4). Primary efficacy endpoints included number of glaucoma medications and intraocular pressure (IOP) at 60 months per group.
Results
Twenty-seven eyes of 22 patients, with a mean age of 76.9±6.1 years were recruited. One eye was medication-free at baseline with IOP=28mmHg and did not reach the 5-year follow-up (this eye was medication-free at 24 months with IOP=16mmHg). Nine eyes were on 1 medication at baseline and on 1.1±0.9 medications at 60 months (n=7; p=0.6); IOP decreased from 18.8±4.6 to 13.7±2.1. Ten eyes were on 2 medications at baseline and on 1±1.4 medications at 60 months; IOP decreased from 20.1±6.5 to 15.6±4.6 (n=5). Five eyes were on 3 medications at baseline and 1.3±0.6 at 60 months (n=3); IOP decreased from 20.2±4 to 13.7±3.1. Two eyes were on 4 medications at baseline and did not reach the 5-year follow-up (both eyes were medication-free at 36 months).
Conclusions
Five years postoperatively, ab-interno canaloplasty performed as a standalone procedure or in combination with cataract surgery achieved a reduction in both the mean number of medications and IOP in patients on 2 or more medications at baseline. In patients on 1 or less medications at baseline the number of medications remained stable while IOP was reduced.