Agreement In Optical Biometry Of A New Swept-Source Optical Coherence Tomography–Based Biometer Versus Optical Low-Coherence Reflectometry

Agreement in optical biometry of a new swept-source optical coherence tomography–based biometer versus optical low-coherence reflectometry

To compare the agreement between a new swept-source optical coherence tomography (SSOCT) biometer (ANTERION, Heidelberg Engineering Ltd, Germany) with that of optical low-coherence reflectometry (OLCR) (Lenstar LS 900, HAAG-STREIT AG, Switzerland).

Biometry measurements were obtain with the use of 2 different devices: the Anterion SSOCT biometer and the OCLR-based Lenstar LS 900. Axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), anterior surface keratmetry (K), lens thickness (LT) and whie-to-white (WTW) were compared between both biometers. The agreement was evaluated with the intraclass correlation (ICC). Bland-Altman method was used to evaluate agreement between both devices and the 95% limits of agreement (95% LoA) were calculated.

One hundred seventy-two eyes of hundred seventy-two patients were included in this study, with a mean age of 69.87 ± 11.87 years (20–95 years). The mean difference between SSOCT and OLCR biometry for AL, CCT, ACD, K1, K2, and LT measurements was 2μm ± 22 (SD), 4μm ± 5 (SD), 29μm ± 82 (SD),  0.02 diopter (D) ± 0.47 (SD), 0.05 diopter (D) ± 0.40 (SD) and -32μm ± 32 (SD), respectively. A very good agreement was obtained for AL, ACD, and LT (CCC >0.95) and a strong agreement for CCT, ACD, K1, K2 and  (CCC>0.72). The 95% LoA were -0.41 to +0.46 for AL, -6  to +14 for CCT, -0.49  to +0.45 for ACD, -0.90 to +0.95 for K1, -0.74 to 0.85 for K2, and -0.94 to 0.30 for LT. 

The Anterion measurements showed good agreement with those of the Lenstar-LS900.