Epithelial Remodeling And Cxl-Line Depth In Keratoconus Following Cxl Combined With Excimer Corneal Reshaping With The Athens Protocol
Published 2022 - 40th Congress of the ESCRS
Reference: PP11.11 | Type: ESCRS 2022 - Posters | DOI: 10.82333/qr0t-nv91
Authors: Anastasios John Kanellopoulos* 1 , Flavia Tzani 2
1ophthalmology,LaserVision Ambulatory Eye Surgery Unit,Athens,Greece;ophthalmology,NYU med School,New York,United States;ophthalmology,LaserVision Ambulatory Eye Surgery Unit,Athens,Greece;ophthalmology,NYU med School,New York,United States, 2Ophthalmology,LaserVision Ambulatory Eye Surgery Unit,Athens,Greece
Purpose
To evaluate epithelial remodeling and CXL-line depth in keratoconic eyes following surface ablation normalization combined with corneal crosslinking (Athens protocol)
Setting
The Laservision.gr Clinical and Research Institute, Athens, Greece
Methods
Fourier-domain anterior segment optical coherence tomography (AS-OCT) was used to obtain in vivo 3-dimensional corneal and epithelial thickness maps and center, superior, inferior, maximum, minimum, mean, midperipheral, and variability data; as well as cross-section assessment of the average depth and width of the CXL derived intrastromal-line visualized.
Results
43 treated keratoconic eyes were evaluated over 2 years The mean overall epithelial thickness (ET) in um changed from 54.6 to 52.6, superior vs. inferior change in um: 56.9 and 52.3 to 53.3 and 52. ET change over cone center 45.1 to 53.2. All differences were statistically significant > 0.01. CXL line mean depth: 265um
Conclusions
These data confirm our previous findings of overall epithelial thickness normalization following CXL with the Athens Protocol. Increase to normal thickness over the cone center along with documentation of a deep CXL-line may serve as confirmation of the result efficacy along with corneal thickness and curvature stability over time.