ESCRS - PP05.08 - : Tomographic And Refractive Characteristics Of Relatives Of Patients With Keratoconus

: Tomographic And Refractive Characteristics Of Relatives Of Patients With Keratoconus

Published 2022 - 40th Congress of the ESCRS

Reference: PP05.08 | Type: ESCRS 2022 - Posters | DOI: 10.82333/e6as-c068

Authors: Rasha mohamed Mousa* 1 , yaser seif 2 , reem mostafa 1

1cornea,memorial institute for ophthalmic research,Cairo,Egypt, 2cornea,Beni-Suef University ,Beni-Suef ,Egypt

Purpose

To evaluate the tomographic and refractive characteristics of relatives of patients with keratoconus

Setting

Memorial institute for ophthalmic research, Beni-Suef University hospital

Methods

An observational cross sectional study was done on both eyes of 248 (496 eyes) relatives of 52 patients diagnosed as Keratoconus, Bilateral corneal topography using (Pentacam Oculus device) with analysis of K1, K2, K max, skewing, anterior elevation, back elevation and thinnest location was done for all cases , the following data were also studied including Uncorrected distance visual acuity(UCVA) in decimal, refraction, corrected distance visual acuity (CDVA)in decimal , slit-lamp bio microscopy and fundus examination

Results

The prevalence of Keratoconus in the relatives of our studied cases was 19/248 (7.7%), 3.2% cases had Forme frost, and 15.3% cases were suspected to have Keratoconus. Normal representing was found in 73.8% of cases. 13.6% of brothers, 4.3% of mothers, 5.6% of sons and 12.1% of sisters had Keratoconus with high significant differences found between them (p=0.001). There were significant differences between relatives regarding presence of refractive errors (p=0.03)

Conclusions

There is high keratoconus prevalence in the first-degree relatives of keratoconus patients. This population is most vulnerable to disease progression, hence the importance of identifying and diagnosing patients in this segment as early as possible.