ESCRS - PP03.09 - Characterization Of Dysfunctional Lens Index And Opacity Grade In A Healthy Population

Characterization Of Dysfunctional Lens Index And Opacity Grade In A Healthy Population

Published 2022 - 40th Congress of the ESCRS

Reference: PP03.09 | Type: Free paper | DOI: 10.82333/yaqc-hs17

Authors: David Pablo Piñero Llorens* 1 , Elena Martínez-Plaza 1 , Pedro Ruiz-Fortes 2 , Roberto Soto-Negro 2 , Carlos J Hernández-Rodríguez 2 , Ainhoa Molina-Martin 1 , Alfonso Arias Puente 2

1Optics, Pharmacology and Anatomy,University of Alicante,San Vicente del Raspeig,Spain, 2Ophthalmology,Vithas Medimar International Hospital,Alicante,Spain

Purpose

To establish normal dysfunctional lens index (DLI) and opacity grade values in a healthy population, and to analyze the relationship between DLI, opacity grade pupil diameter, and wavefront aberrations.

Setting

Department of Optics, Pharmacology and Anatomy. University of Alicante, Spain

Department of Ophthalmology. Vithas Medimar International Hospital, Alicante, Spain

Methods

A total of 61 volunteers (102 eyes) classified into subjects<50 years (group 1) and subjects≥50 years (group 2) were enrolled. DLI, opacity grade, pupil diameter, and corneal, internal and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Statistical analysis was performed, considering all, right and left eyes in each group.

Results

Mean DLI was 8.89±2.00 and 6.71±2.97 for groups 1 and 2, respectively; being significantly higher for group 1 in all and right eyes (both p<0.001). DLI correlated with age (Rho=-0.41, p<0.001) and pupil diameter (Rho=0.20, p=0.043) for all eyes, and numerous internal and ocular root-mean square HOAs for right, left and all eyes (Rho≤-0.25, p≤0.001). Mean opacity grade was 1.21±0.63 and 1.48±1.15 for groups 1 and 2, respectively, with no significant differences between groups (p≥0.29). Opacity grade significantly correlated with pupil diameter for right and all eyes (Rho≤0.33, p≤0.013), and with some ocular root-mean square HOAs for right and all eyes (Rho≥0.23, p≤0.020).

Conclusions

Normal DLI and opacity grade values in subjects below and above 50 years are provided as a reference for clinicians and researchers. DLI could be used complementary to other diagnostic measurements for assessing the dysfunctional lens syndrome. The algorithms used to calculate both indexes may be based on pupil diameter and HOAs.