Corneal Epithelium And Anterior Stroma Analysis After Trans-Prk By Confocal Microscopy.
Published 2022
- 40th Congress of the ESCRS
Reference: PO501
| Type: Free paper
| DOI:
10.82333/5qbj-jm66
Authors:
Manuel Ramirez* 1
, Emmanuel Cabrera 1
, Everardo Hernandez-Quintela 2
, Guillermo Dewit 1
1Cornea,APEC,Mexico City,Mexico, 2Comprehensive Ophthalmology,Wilmer Eye Institute ,Baltimore,United States
Purpose
To evaluate confocal microscopy findings after trans-PRK.
Setting
High referral ophthalmology hospital
Methods
16 eyes of 8 patients with mild to moderate myopia with or without mild astigmatism were included and treated with StreamLight™ tPRK with the WaveLight® EX500 excimer laser (Alcon Laboratories, Forth Worth, TX, USA). A central scan of the total corneal thickness was taken with the confocal microscope Confoscan 4® (Fortune Technologies, Italy) before and one month after treatment. Corneal epithelium thickness and morphology were evaluated, depth of activated keratocytes was measured, and corneal stroma ablated was calculated by the difference between preop vs. postop total stromal thickness. All measurements and morphology analyses were done using the NAVIS software V. 3.5.0 (NIDEK, Multi-Instrument Diagnostic System, Japan).
Results
Corneal epithelium thickness before surgery was 45.4 ± 5.4 vs. 44.6 ± 5.3 µm after surgery (P=.463). Epithelium morphology was similar between before vs. after surgery findings. One month after treatment, the mean depth of activated keratocytes was 22.9 ± 7.8 µm (range 10 to 33). Mean corneal stroma ablated was 35.9 ± 20.2 µm (range 10 to 67).
Conclusions
Corneal epithelium showed similar morphology and not significant difference in thickness one month after trans-PRK compared to preop findings; corneal stromal findings are similar to PRK previous reports.