Six Months Outcome Of Single- Step Transepithelial Photorefractive Keratectomy In Low To High Myopia With Large Optical Zones

To evaluate the safety, efficacy and refractive outcomes of Trans-Photorefractive Keratectomy (TPRK) with Smart Pulse Technology (SPT, SCHWİND eye-tech-solutions, GmbH, Kleinostheim, Germany) in treatment of low, moderate and high myopia with large ablation zones.

Veni Vidi Eye Center, Istanbul, Turkey

This was a retrospective, non-randomized study evaluating the outcome of TPRK with SPT in eyes with low (≤-3.00D), moderate (-3.00 to -6.00D)and high myopia (≥-6.00D) with or without astigmatism. 198 eyes of 100 patients were included in the study. 109 eyes were low myopics, 74 eyes were moderate, and 15 eyes were high myopics. All patients were followed for six months after the treatments. All eyes underwent treatments with Schwind Amaris 1050 RS with aberration free profile and with optical zones of 7.0 mms or more. Operational parameters, preoperative and the postoperative 6th month’s monocular visual acuities and refractive, topographic, aberrometric outcomes, the safety and efficacy indices, and corneal haze grading were analyzed.

Postoperative UDVA was higher in low myopics than the moderate and high myopics (p=0.003; p=0.032). The CDVA was higher in low myopics than the moderate myopics (p=0.001). The mean safety index was higher in the moderate myopics (1.02 ± 0.10) than the high myopics (0.96 ± 0.15) (p=0.04). There was no difference for the mean safety index between low (1.02 ± 0.1 ) and high (0.96 ± 0.15) miyopics (p=0.114). The mean efficacy index was not different in the three groups (p>0.05). The preoperative corneal HOAs were not different in the three groups (p>0.05). The postoperative HOAs were lower in the low myopics than the moderate and high myopics (p=0.001; p=0.011). There was no difference between the moderate and high myopics (p=0,102).

Our study demonstrates an acceptable safety and efficacy of outcomes in low, moderate and high myopic eyes which have undergone TPRK treatments with SPT using large optical zones. After six months, the refractions and visual acuities improve. Trans-PRK appears to be a safe and effective procedure for all types of myopia.