ESCRS - PO427 - Comparison Of Choroidal Thickness Measured By Early Treatment Diabetes Retinopathy Study (Etdrs) Subfield And Manual Line Measurement In Swept-Source Oct. Relation Between Subfoveal Choroidal Thickness And Several Ocular Parameters.

Comparison Of Choroidal Thickness Measured By Early Treatment Diabetes Retinopathy Study (Etdrs) Subfield And Manual Line Measurement In Swept-Source Oct. Relation Between Subfoveal Choroidal Thickness And Several Ocular Parameters.

Published 2022 - 40th Congress of the ESCRS

Reference: PO427 | Type: ESCRS 2022 - Posters | DOI: 10.82333/s4ys-1366

Authors: Neus Burguera Giménez* 1 , Celeste Briceno-Lopez 2 , Amparo Díez-Ajenjo 3 , Mª José Luque-Cobija 3 , Mª Carmen García-Domene 3 , Noemi Burguera 4 , Cristina Peris-Martínez 5

1Cathedra Alcon-FISABIO-UVEG. Cornea and anterior segment unit,FISABIO Oftalmología Médica,Valencia,Spain;Department of Optics, Optometry and Vision Sciences ,University of Valencia,Burjassot (Valencia),Spain, 2Cathedra Alcon-FISABIO-UVEG. Cornea and anterior segment unit,FISABIO Oftalmología Médica,Valencia,Spain;Department of Optics, Optometry and Vision Sciences,University of Valencia,Burjassot (Valencia),Spain, 3Department of Optics, Optometry and Vision Sciences,University of Valencia,Burjassot (Valencia),Spain;Cathedra Alcon-FISABIO-UVEG. Cornea and anterior segment unit,FISABIO Oftalmología Médica,Valencia,Spain, 4Ophthalmology department,Q vision, Vithas Virgen del Mar Hospital,Almería,Spain, 5Cathedra Alcon-FISABIO-UVEG. Cornea and anterior segment unit,FISABIO Oftalmología Médica,Valencia,Spain;Surgery Department, Ophthalmology, School of Medicine,University of Valencia,Valencia,Spain

Purpose

To compare subfoveal choroidal thickness (SCT) obtained from the topographic map of choroidal thickness in ETDRS-style grid and the manual line measurement in healthy eyes and to evaluate the influence of several ocular parameters over SCT.

Setting

Cathedra Alcon-FISABIO-UVEG

FISABIO Oftalmología Médica

University of Valencia

Methods

Prospective and non-randomized study with 40 eyes of 40 healthy volunteers aged between 18 and 45 years. SCT was automatically obtained from ETDRS grid using the 12mm line scan pattern. Then, SCT was manually measured as the distance between the posterior edge of the hyper-reflective retinal pigment epithelium (RPE) and the choroidal junction using the single line scan pattern. Both SCTs were measured using swept-source OCT (DRI-1 Atlantis, Topcon Medical System, Japan). Only eyes with axial length (AL) between 22-26mm and spherical equivalent (SE)<-3.00D were included. The t-test was used to compare SCT between the two scanning methods. Multiple linear regression was performed to evaluate the influence of gender, age, SE and AL over SCT.

Results

Mean age was 29.85 ± 7.10years, mean SE was -0.70 ± 1.31D and mean AL was 23.52 ± 0.92mm. SCT was thinner at central ring, 309 ± 62μm, compared to the manual SCT measurement, 335 ± 66μm. The two different scanning protocols showed significatively differences, mean difference= 25.55 ± 27.07μm (95%CI, 16.90-34.21), t(39)=5.97, p=0.000. Similar SCTs were observed between women and men at the central subfield of the choroidal thickness map (women 335 ± 62μm vs. men 331 ± 84μm) and with manual measurement (women 311 ± 58μm vs. men 302 ± 80μm). Multiple linear regression showed that SCT was not significantly associated with either gender, age, SE or AL, although a trend for thinner SCT associated with longer AL was observed (B= -13.2μm), p>0.05. 

Conclusions

Choroidal thickness measured by using ETDRS grid reported SCT significantly thinner than manual measurement. Both methods should be independently considered. SCT did not varied significantly with gender, age, SE and AL.